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A near-patient approach to combat post-partum hemorrhage by Catherine Pedrosa Fibrinogen is an essential part of the blood clotting process, and rapid testing of plasma fibrinogen concentrations aids decision-making in critical care situations, notably in postpartum hemorrhage. In 2020, around 1000 women in the World Health Organization European Region died owing to complications related to […]
The use of immunoassays is widespread in clinical lab testing as these assays have inherent high specificity and high sensitivity, and are very amenable to high-throughput formats. These attributes make them particularly useful for the measurement of low concentrations of low molecular weight drugs, metabolites or biomarkers that indicate disease diagnosis or prognosis. Although there […]
Pancreatic cancer is a devastating disease, usually first diagnosed at a late stage when the opportunity for the most effective therapy has been missed, and survival rates have not improved for decades. Early detection of the disease is crucial for giving patients the chance of therapy, but, so far, the search for serum protein biomarkers […]
Gilead Sciences announces positive results from Veklury and obeldesivir trials Gilead Sciences, announced positive results from several COVID-19 clinical and real-world evidence studies presented at ECCMID. A Phase 3 clinical study demonstrated that Veklury (remdesivir) was generally well tolerated in people with moderate to severe renal impairment. Additional data includes a retrospective real-world study which […]
Axcella Therapeutics presents results from Phase 2a clinical trial of AXA1125 for treatment of Long COVID Fatigue Axcella Therapeutics – a clinical-stage biotechnology company pioneering novel approaches to treating complex diseases using multi-targeted endogenous metabolic modulator (EMM) compositions – gave two oral presentations of results from the Phase 2a clinical trial of AXA1125 in the […]
Shionogi demonstrates efficacy of cefiderocol against difficult-to-treat Gram-negative bacterial infections At ECCMID 2023, Osaka, Japan-based Shionogi announced key data for cefiderocol, an innovative siderophore cephalosporin, including new real-world evidence demonstrating its efficacy against some of the most difficult-to-treat Gram-negative bacterial infections.
ELITech showcases new high throughput sample-to-result instrument for molecular diagnostics Also at ECCMID, ELITech Group unveiled the upcoming launch of a new high throughput sample-to-result instrument for molecular diagnostics.
Influential ECCMID 2023 sees numerous scientific presentations The 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) took place in Copenhagen, Denmark, 15-18 April 2023. With around 14,000 professional attendees ECCMID is the largest international meeting of clinical microbiologists and infectious diseases specialists. The event included a comprehensive scientific programme, an industry programme and […]
Faster throughput – together | New streamlined solution for immunosuppressant analysis by LC-MS/MS by Mikaël Levi To face increasing demands on their time and resources, chemical laboratories need easier-to-handle solutions with faster turnaround times, lower costs per sample and full compliance with ever-stricter regulatory standards. Recent work by Alsachim using Shimadzu equipment and software has […]
by Dr Jacqueline Gosink Biomarkers and preanalytics in Alzheimer’s disease Analysis of biomarkers such as amyloid-beta peptides and tau proteins in cerebrospinal fluid (CSF) is nowadays a core criterion in Alzheimer’s disease diagnostics. Test methods such as ELISA and chemiluminescence immunoassay enable robust and reproducible measurement of the analytes in patient CSF samples. Recommendations for […]
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