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Innovative tube-in-plate reactor enhances flow chemistry capabilities

Uniqsis, a specialist in mesoscale continuous flow chemistry systems, has unveiled a novel Tube-in-plate (TIP) reactor designed to address the challenges faced in synthetic chemistry experiments requiring efficient heat transfer. This new development offers a cost-effective alternative to traditional glass static mixer (GSM) reactor blocks, particularly for applications where static mixing is not a primary concern.

Addressing limitations in existing technology

Whilst GSM reactor blocks are known for their efficiency in producing turbulent mixed reagent streams and providing excellent heat transfer due to their narrow internal channels and large surface area, they can be prone to blockages. The new TIP reactor aims to overcome this limitation whilst maintaining optimal performance for certain applications.

The TIP reactor incorporates narrow bore, perfluoro polymer tubing embedded in channels cut into an aluminium block. A glass cover plate is utilised to stabilise the internal temperature of the reactor whilst retaining visibility. This design allows for easy removal and replacement of the tubing should it become blocked or contaminated, addressing a key issue faced with traditional GSM blocks.

With an internal volume of 9.5 ml, the single layer large format TIP reactor demonstrates versatility in its application. It is suitable
for both photochemistry and conventional thermally mediated reactions, offering researchers a flexible tool for various experimental setups.

Compatibility and cost-effectiveness

The new TIP reactors are fully compatible with Uniqsis’ existing range of reactor modules, including HotChip, ColdChip, PhotoChip and Polar Bear Plus GSM. This compatibility ensures seamless integration into current laboratory setups, whilst providing a more cost-effective solution compared to ‘large format’ GSMs for reactions where static mixing is not critical.

For more information on Uniqsis’s Tube-in-plate reactors, visit: www.uniqsis.com

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