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Methylation landscape as a general test for cancer

DNA methylation at the cytosine of CpG dinucleotides is a key form of epigenetic regulation of gene expression and aberrant hypermethylation of the promoter regions of certain genes has been identified in many cancers. The ability to analyse methylation status from non-invasively collected samples (such as saliva, sputum, stool and urine) as well as circulating […]