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4011

Avacta Group collaborates with Adeptrix to develop a high throughput Covid -19 antigen test

UK-based Avacta Group, the developer of Affimer biotherapeutics and reagents, will collaborate with US-based Adeptrix to develop a high throughput Covid -19 antigen test using Adeptrix’s proprietary bead-assisted mass spectrometry (BAMS) platform. The Affimer-based BAMS coronavirus antigen test that will provide clinicians with a significant expansion of the available testing capacity for Covid-19 infection in […]

4012

BIOHIT supplies COVID-19 detection kits in the UK

BIOHIT Healthcare is distributing test kits for the diagnosis of both current and past COVID-19 infections to help in the fight against coronavirus in the UK. The new product line includes the MutaPLEX® Coronavirus kit from Immundiagnostik AG (IDK) – a real-time RT-PCR assay to screen for infected individuals – and Epitope Diagnostics Inc’s (EDI’s) […]

4013

IVD assay iAMP Covid-19 Detection Kit receives CE Mark

Fujirebio Europe has received the CE mark for the molecular IVD assay iAMP Covid-19 Detection Kit from its partner Atila Biosystems. The qualitative detection kit is based on real-time fluorescent reverse transcription isothermal amplification, eliminating the need for RNA extraction. The detection kit was also granted Emergency Use Authorization by the US Food and Drug […]

4014

NanoPass shares proprietary MicronJet microneedle to assist in development of a Covid-19 vaccine

NanoPass is sharing its proprietary MicronJet microneedle device with leading vaccine and immunotherapy companies around the world to assist in development of a Covid-19 vaccine. The NanoPass device targets immune cells of the skin by harnessing the skin’s potent immune system to improve vaccines and/or to dramatically reduce the dose while achieving the same immunity. […]

4015

Volunteer laboratory network launched in UK to expand Covid-19 testing

The UK-based Covid-19 Volunteer Testing Network launched April 9 to provide essential additional testing capacity to front-line workers. The project, started by Mike Fischer CBE, helps small laboratories convert to run critical antigen testing and identify Covid-19 cases among local healthcare workers – at no cost to Government. The UK has thousands of small laboratories […]

4016

Better health care through mass spectrometry – better mass spectrometry through standardization

by Prof. Michael Vogeser, Dr Judy Stone and Prof. Alan Rockwood While analytical standardization and metrological traceability are well-defined terms, ‘methodological standardization’ in clinical mass spectrometry is still in a developing stage. We propose a framework that facilitates the widespread implementation of this highly complex and very powerful technology and is based on two pillars […]

4017

Consider moving average quality control when internal control is insufficient or inefficient – the time is now!

by Dr Huub H. van Rossum Recently, significant improvements have been made in understanding and applying moving average quality control (MA QC) that enable its practical implementation. These include the description of new and laboratory-specific MA QC optimization and validation methods, the online availability thereof, insights into operational requirements, and demonstration of practical implementation. IntroductionMoving […]

4018

Acute pancreatitis biomarkers: to many or too few?

by Dr Allison B. Chambliss The diagnosis of acute pancreatitis has long relied on elevations in serum amylase or lipase. Recent test utilization efforts have called f or the discontinuation of amylase in acute pancreatitis, favouring the higher specificity and longer elevation of lipase. However, neither biomarker correlates with disease severity, and early recognition of […]

4019

Sensitive and precise multiplex assays enable accurate classification and surveillance of tumours

by Prof. Godfrey Grech, Dr Stefan Jellbauer and Dr Hilary Graham Understanding the molecular characteristics of tumour heterogeneity and the dynamics of progression of disease requires the simultaneous measurement of multiple biomarkers. Of interest, in colorectal cancer, clinical decisions are taken on the basis of staging and grade of the tumour, resulting in highly variable […]

4020

Parallel genetic testing for primary lactose intolerance and hereditary fructose intolerance

by Dr Jacqueline Gosink Gastrointestinal complaints are very common and can be difficult to diagnose. Among the many causes are genetic deficiencies in digestive enzymes. Molecular genetic analysis of polymorphisms in the patient’s DNA can determine if inborn enzyme deficits are behind the digestive problems, aiding differential diagnostics. Primary lactose intolerance, for example, is associated […]