Lab automation can help handle increasing workloads from the growing demand for in vitro diagnostic testing and allows better use of personnel. The circular track and modular design of the Aptio Automation platform ensures that it can be adapted to nearly any lab or testing environment. It also offers connectivity to Siemens’ portfolio of automation-ready analysers, thus facilitating a multidisciplinary approach to testing. The point-inspace aspiration feature helps streamline workflow by reducing the need to aliquot (or divide) samples, and its puck-based system with radio frequency identification enables individual sample routing and tracking, along with STAT prioritization. The system delivers comprehensive analytics via powerful, centralized information technology, while having the flexibility to provide pre- and post-analytical capabilities. The company’s CentraLink data management system facilitates efficient sample flow, auto-verification, quick access to samples and proactive quality control. This can also be customized for the end user, which speeds up system access and supports error reduction.
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With 360° rotation, the 6-position pipette work station, TwisterTM universal 336, enables quick and easy instrument selection. Storage space is provided for six pipettes of most brands, and the interchangeable discs are available in a choice of seven translucent colours. The unit is simple to disassemble and reassemble for cleaning.
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The OneWell Plate is a cell culture dish with a compartment that is particularly suitable for cultivating and analysing bacteria. Its automation-friendly plate format enables automated replication of bacteria colonies. The rectangular, stackable plate allows highly efficient use of incubator space. A model with a surface hydrophilized by physical treatment is available for adherent cell culture. The FourWell Plate, with four individual chambers, offers space for four slides, thereby enabling parallel experiments. Cell and tissue samples cultivated on these slides can be supplied with fresh medium quickly and easily and examined directly under a microscope. Semi-circular cavities in the base of each well facilitate the removal of slides with tweezers, and spacers prevent the slides from slipping to the edge of the well and covering these cavities. Both plates, made of transparent polystyrene, are sterile and free of detectable pyrogens, human DNA and DNases/ RNases. Their external dimensions comply with ANSI microplate standards and the plates can be used with a variety of automated systems. A bevelled edge on lid and dish ensures the lid can only be applied in one direction. The plates can also be used as multi-purpose containers for washing membranes (Southern, Northern and Western blots), for example.
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Delivering increased sensitivity, the Triple Quad 6500 and QTRAP 6500 systems are next-generation mass spectrometers designed for those who need to push the limits of quantitation in complex matrices while maintaining reproducibility and robustness. With new multi-component Ion- Drive technology increasing the generation, transmission and detection of more ions, the instrument delivers sensitivity enhancements with no compromise in mass range. This is made possible by significant improvements in the ionization source through the new Turbo V source, enhancements in the ion transmission stage with the novel QJet guide, and a 20x increase to the detector dynamic range with the High Energy detector. The 6500 platform is also compatible with the novel SelexION Technology, which delivers a new dimension of selectivity in differential ion mobility spectrometry for quantitative and qualitative analysis. The 6500 series is ideally suited to a variety of applications, including drug discovery and development in regulated laboratories; peptide quantitation as well as biomarker verification in biomedical research; and clinical research in endocrinology laboratories.
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Cryogenic sample storage requires tubes that can withstand the pressures of being frozen in liquid nitrogen and thawed again. Providing biological sample storage in temperatures as low as -196oC, the Cryo- Clear vials feature a unique screw cap that is co-moulded with thermoplastic elastomer eliminating the need for silicone o-rings. This special process prevents the risk of sample contamination and provides the purest and most leak-resistant vial available. The tubes are certified 95kPA to provide a 100% leak-proof seal. Each production lot is certified by an independent laboratory to be free of human DNA, DNase, RNase, Pyrogens and ATP, and the vials are manufactured, assembled and packaged in a Class 7 clean room and never exposed to outside contaminants. Each tube is printed with a unique 128-format barcode for automated data collection, accurate sample inventory and to hide the identity of the sample. The vials are available with internal and external threads and with round or self-standing interlocking bottoms.
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