C248 Genalyte

One-step screening for common connective tissue disease autoantibodies

Created to simultaneously screen for several of the most common autoantibodies found in autoimmune connective tissue disorders, such as systemic lupus erythematosus (SLE), the Maverick ENA 4 and ENA 6 assay kits are the first available for the Maverick Detection System. Their simplified one-step workflow delivers accurate results in 15 minutes and can be run using very small volume samples from a variety of matrices, including serum and plasma. The ENA 4 assay tests for the presence of four of the most commonly measured extractable nuclear antigens (ENA), including SS-A, SS-B, Sm and RNP, while the ENA 6 assay includes two additional commonly measured antigens–Scl-70 and Jo-1, so covering six multiplexed tests per sample. The assay results are highly reproducible, show excellent correlation to ELISA and are up to ten times more sensitive. The assays are available to participants in the company’s Early Access programme, which enables scientists to gain pre-launch access to multiplexed autoantibody assays and the Maverick Detection System. This uses a proprietary chip based on silicon photonics to simultaneously analyse multiple proteins from a single small sample. The multiplexing technology simultaneously screens for the detection of autoantibodies using a one-step process that eliminates the washes, incubations, reagents and processing steps typically associated with other technologies. Semi-quantitative results are reported for each analyte, eliminating the need for reflex testing. The assays are simple to use and rapid – results are available in only 15 minutes, including just two minutes of hands-on time. A number of higher plexed assays for autoimmune diseases, including rheumatoid arthritis, celiac disease and others, are also in development.
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C261 MPbiomedicals Multisure Option 07

Immunochromatographic assay for hepatitis C virus

It has been estimated that 3 to 4 million people are infected with hepatitis C virus (HCV) each year. Four out of five people develop chronic hepatitis C infection, which can subsequently lead to liver cirrhosis and/or liver cancer. Early detection is the key to combating hepatitis; hepatitis C infection can be effectively controlled or treated if it is diagnosed early. HCV ELISA and rapid tests are widely used for screening and diagnosis of hepatitis C infection. These tests use specific antigens from the structural region and non-structural regions of the virus to detect the presence of antibodies to HCV. Reactive samples from screening tests are then confirmed by immunoblot assay. The MULTISURE HCV Antibody Assay is a qualitative immunochromatographic assay, intended for the detection of antibodies specific to HCV core, NS3, NS4 and NS5 antigens. The test is based on the capture of HCV antibodies using immobilised HCV recombinant antigens on a nitrocellulose membrane and the subsequent detection of captured analyte using goat anti-human IgG conjugated to colloidal gold. It has been developed from the patented reverse-flow test platform, giving greater sensitivity and easy-to-read visual signals. Similar to a confirmatory immunoblot, this assay can detect and differentiate the structural and non-structural HCV proteins. The test result pattern may, therefore, offer information such as the possible phase of the Hepatitis C infection. This simple and rapid assay takes only 15 minutes and is easy to use. It is an instrument-free platform and does not require highly trained personnel to perform the test, thus making it suitable for use in a point-of-care setting. With shortened turnaround time, patients are diagnosed early and have wider access to treatment and care.

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KZ DocUReader 2

Performing urinalysis in the easiest and most efficient way

The new DocUReader 2 system is designed for physician’s offices and smaller laboratories to read and evaluate the LabStrip U11 Plus urine test strips with 50 samples / hour throughput.   The compact design of this lightweight instrument offers the broadest features and highest flexibility available on any desktop size urine analyzer. Auto start functionality and advanced, patented detection technique guarantee fast and accurate results. User friendly software ensures flexible testing and reporting options as well as effective data management. Manual entry of color and turbidity data improves clinical utility. Automated result and worklist transmission is enabled by LIS connectivity. More accurate data entry and reduced transcription errors can be achieved by optional barcode reader and external keyboard. Continuing the mission of the previous DocUReader, the new instrument features simple operation, cost efficiency, and high quality. The DocUReader 2 Pro additionally provides enhanced quality control and connectivity capabilities, operator management, and extended memory capacity.

More info – contact: sales@e77.hu
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C284 Astra

High quality diagnostics for personalized medicine

Extending the company’s range of diagnostic testing solutions, the kits enable DNA extraction and the identification of polymorphisms in genes linked to disease or drug metabolism. The kits are real time PCR-based, and validated on multiple PCR instruments from leading manufacturers. These include thrombosis kits for the detection of polymorphisms in F5 and F2 genes, supporting disease management. The drug sensitivity kits determine an individual’s susceptibility to indirect anticoagulants and other drugs, including polymorphisms in CYP2C9, VKORC1, CYP2C19 genes. This knowledge is important in correct dosage prescription, which can vary hugely across genotypes. The Multi DNA extraction kit provides fast, easy extraction from various sample types, including serum, plasma, dry blood spots, urine, saliva and epithelial cells.
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Random access benchtop analyser

The RX daytona plus provides high quality testing on a compact, easy to use clinical chemistry analyser with accurate results. A fully automated, random access, benchtop analyser, it features a throughput of 450 tests per hour including ISE. Its comprehensive and flexible test menu allows the consolidation of a wide range of routine and specialized tests including routine chemistries, specific proteins, therapeutic drugs and drugs of abuse. Dedicated RX support teams provide technical support as needed, maximizing laboratory efficiency.
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C263 DiaSource

1,25 (OH)2 Vitamin D ELISA

The hormone 1,25 dihydroxy vitamin D is formed in the kidney and has important functions in calcium metabolism; hence impaired kidney function can result in a decrease in 1,25 dihydroxy vitamin D levels and the development of renal osteopathy, which is characterized by osteomalacia and osteitis fibrosa. This company’s assay development programme is focusing specifically on new vitamin D assays. After the recent launch of the 25-Hydroxyvitamin D Total RIA and ELISA assays based on patented monoclonal antibodies manufactured in-house, a new easy-to-use 1,25 dihydroxy Vitamin D ELISA is launched. This ELISA is specifically designed to be used manually as well as on open automated systems. As the total assay time is less than 6 hours, the patient’s results will be available the same day. The assay has been validated on the Stratec GEMINI open ELISA automated analyser (Stratec Biomedical GMBH – Germany) and a validated protocol will be made available to all Stratec GEMINI users.
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C279 SFRI

Blood cell counter for small labs

This compact 30 test/hour analyser is designed for daily use in labs with low throughput and offers all the qualities of a 60 test/hour instrument at an aff ordable cost. The COUNTENDER 30 features 20 parameters, 3 histograms and excellent CVs. It outclasses most 60 tests/hour analysers in terms of performance and quality of results and is top of its category, providing results in under 2mins. It also features very low reagent consumption. Combining simplified maintenance and long shelf-life of the company’s reagents (up to 36 months), the blood cell counter has low servicing requirements and enables signifi cant cost per test reduction for labs.
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C267 BioSystems

Reagent for CO2 measurement

Analysis of CO2 is performed as part of an electrolytic analysis in the investigation of acid-base disorders, monitoring kidney disease (bicarbonate absorption function) or hypertension. In the body, 95% of CO2 is present as HCO3- (bicarbonate). Elevated or low levels of HCO3-may indicate a variety of disorders. The Carbon Dioxide Reagent is available in diff erent presentations, as well as Dioxide Standard and Carbon Dioxide Control.
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C280 EKF 1203EKF BHB Kit

Improved detection of clinically significant ketosis

The β-Hydroxybutyrate LiquiColor reagent system assays levels of the ketone β-hydroxybutyrate (BHB) in serum and plasma for the clinical diagnosis and monitoring of diabetes mellitus, alcoholism, glycogen storage disease, high fat/low carbohydrate diets, pregnancy, alkalosis, ingestion of isopropyl alcohol and salicylate poisoning. As BHB is the main ketone produced during ketosis (~78%), the blood assay provides a better tool than the nitroprusside test strips commonly used for the detection of ketone bodies in urine, which only detect 22% of ketones present. BHB also demonstrates excellent stability, making it the most reliable indicator of clinically relevant ketosis and ketoacidosis. This reagent produces quantitative and objective results and provides an excellent tool for diff erentiating metabolic acidosis and monitoring therapy. Its precise and sensitive quantitative results enable earlier detection of ketosis and faster patient treatment, thus improving Emergency Room and Critical Decision Unit throughput and efficiency.
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C274 Diasys

Automatic intestinal parasite analysis system

The automated parasite analysis system, Parasys, provides up to 4-fold greater sensitivity than the manual technique and in a fraction of the time. It standardizes laboratory protocol and morphology is improved, as new flow cell provides a 3D view of the organisms without the distortion that is usually created by the pressure of a coverslip. Lab staff gain health and safety benefits because they do not come into contact with hazardous samples or reagents.
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