Clinical laboratory International (CLI)
The leading international magazine for Clinical laboratory Equipment for everyone in the in vitro diagnostics field and related disciplines.
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panglobal2026-01-15 09:36:492026-01-15 09:36:49Revvity unveils AI platform for molecular discovery
Measurement of steroid hormones
, /in Featured Articles, Therapeutic Drug Monitoring /by panglobalChallenges and applications Measuring concentrations of steroid hormones – specifically androgens and estrogens – is challenging because they are present at very low concentrations and are structurally very similar. CLI chatted to James Hawley to find out more about these difficulties and how the assays are beginning to be used to measure testosterone levels in […]
Evaluation of AI colon biopsy screening tool errors
, /in Featured Articles, Digital Imaging /by panglobalBackground Lenses and microscopes The use of microscopy has been pivotal to the diagnosis of disease for hundreds of years. The earliest evidence for the use of magnification dates back to the 5th century BC and the use of simple microscopes and lenses in spectacles in the 13th century AD. Compound microscopes appeared in Europe […]
Serology testing can allow a no-biopsy approach to coeliac disease diagnosis
, /in Featured Articles, Gastrointestinal Disorders /by panglobalThe global prevalence of celiac disease is around 1%, although it is likely that many people remain undiagnosed. Historically, diagnosis was usually made in younger children, but the condition can develop at any age and the incidence is increasing in adults. Traditionally, a biopsy has been required to confirm diagnosis, but increased endoscopy waiting times […]
Anti-laminin β4 – a new autoantibody marker in pemphigoid disease
, /in Autoimmunity & Allergy, Featured Articles /by panglobalLaminin β4 (lamβ4) has been identified as a novel target antigen in anti-p200 pemphigoid, a rare autoimmune disease manifesting with subepidermal blisters. Anti-lamβ4 antibodies bind to the region of the dermal–epidermal junction and demonstrate pathogenic effects. A recombinant-cell indirect immunofluorescence assay has been developed for specific detection of anti-lamβ4 antibodies.