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Archive for category: Product News

Product News

C426 Haematex DOAC STOP product image

Direct oral anti-coagulant adsorbent

, 26 August 2020/in Product News /by 3wmedia

DOAC Stop eliminates all direct oral anti-coagulants (DOACs) from test plasmas, making it possible to obtain valid results for all conventional coagulation assays and tests for thrombophilia.  This adsorbent has amazing affinity for DOACs but no effect on clotting proteins, antibodies or heparins. Because it extracts only DOACs, a clotting test result which remains abnormal can be assumed to have other causes.  DOAC Stop minitabs (one/ml) disperse readily in plasma and take less than 5 minutes to bind more than 95% of DOACs in most cases. The adsorbent is quickly removable after it has done its work by centrifugation.  The minitabs work equally well on direct thrombin inhibitors (eg dabigatran) and those against FXa (rivaroxaban, apixaban, edoxaban) and have no effect on heparins or warfarin plasmas.  In most cases DOAC levels can be estimated quickly from the ratio of clotting test results before to after the extraction via an appropriate calibration curve. The best results are obtainable using high phospholipid dRVVT or APTT reagents.

HAEMATEX
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/C426_Haematex_DOAC_STOP_product_image.jpg 529 424 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:52Direct oral anti-coagulant adsorbent
Pantelis Vlachos

Cytel announces East Alloy for easy access to verified Bayesian methods

, 26 August 2020/in Product News /by 3wmedia

Cytel Inc., an advanced analytics leader providing sophisticated quantitative insights to decision-makers in clinical investigation, has launched East Alloy. This new platform is a web-native extension of Cytel’s world-renowned East software for adaptive clinical trial design and analysis.
By leveraging the speed of cloud computing and the pace of SaaS delivery, East Alloy enables easy implementation of computationally intensive Bayesian methods that may be otherwise impractical. The launch of East Alloy builds on Cytel’s time-tested record of delivering cutting-edge Bayesian tools and engines to the pharmaceutical industry for optimized clinical trials.
Bayesian methods are of growing interest to the drug development industry, as they allow clinical investigators to leverage historical trial data as well as learnings from new data as it accrues throughout a trial. The result is better-informed decision making, greater program flexibility, and the ability to run smaller, more resource-efficient trials.
“Our longstanding dedication to adaptive Bayesian approaches means we’re perfectly placed to meet and exceed the growing innovation needs of the pharmaceutical sector,” said Pantelis Vlachos, Director and Strategic Consultant at Cytel. “But it’s key to ensure our customers can practically implement this kind of innovation. East Alloy, reinforced by industry-leading verification, training, and support from Cytel experts, means users can sustainably adopt Bayesian designs to expedite clinical development and overcome uncertainty without compromising scientific rigor.”
The release of East Alloy follows the launch of East Hosted in 2019, which brought Cytel’s East software into the cloud for the first time to simplify the deployment of software updates, reduce on-premise IT burden, and ultimately broaden access to Cytel’s trial design and analysis engines.

  • For more information about Cytel, visit: https://www.cytel.com

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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/Pantelis_Vlachos.png 772 696 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:28Cytel announces East Alloy for easy access to verified Bayesian methods
iMLayer

Revolutionary sample preparation for MS imaging

, 26 August 2020/in Product News /by 3wmedia

Shimadzu’s iMLayer boosts spatial resolution for MS imaging experiments. It enables reproducible matrix coating with small crystals and minimizes delocalization effects. Get a crystal clear view of microstructures in your sample.
Features

  • Creation of fine matrix crystals by unique matrix vapor deposition technology (sublimation) enabling high resolution MS imaging experiments
  • Minimized delocalization effects compared to conventional spraying method due to sublimation technique
  • Good reproducibility through automated matrix layer thickness control
  • Simple touch pad operation making the easy-to-use standalone instrument a sample preparation tool for any MS imaging experiment

For information please click here.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/iMLayer.jpg 737 958 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:37Revolutionary sample preparation for MS imaging
Bio Rad FCP CLI October

Quality indicator monitors instrument HIL interference detection

, 26 August 2020/in Product News /by 3wmedia

Although your instruments may automatically detect HIL interferences, shouldn’t the lab’s QC program include pre-analytical checks to monitor instruments’ ability to detect them? Studies show that interferences from hemolysed, icteric or lipemic (HIL) specimens are amongst the most common pre-analytical errors.  Liquichek Serum Indices is a quality indicator intended for use as part of laboratory interference testing to monitor an instrument’s ability to detect these three types of samples. Replicating relevant concentrations of HIL interferences using human-sourced materials will allow confidence in the instrument’s performance. With Bio-Rad’s Unity Interlaboratory Program, the user is able to compare instrument responses among peer groups to help avoid costly test repeats. https://tinyurl.com/yxpmoe2e
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/Bio-Rad_FCP_CLI_October.jpg 387 542 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:46Quality indicator monitors instrument HIL interference detection
PRODUCT CLI ELITECHGROUP

ELITechGroup’s Staining Technology Expands with Aerospray® Cytology Slide Stainer/Cytocentrifuge

, 26 August 2020/in Product News /by 3wmedia

Logan, UT, January 17, 2020 – ELITechGroup Inc., recognized worldwide as slide staining and cytocentrifuge technologic pioneers and innovators, with nearly 30 patents, over the 35-year lifespan of Aerospray staining technology, announces the launch of the Aerospray Cytology Slide Stainer Cytocentrifuge. The ELITechGroup’s Aerospray Cytology Slide Stainer/Cytocentrifuge automates the preparation and staining of liquid based cytology specimens to facilitate the examination of an array of cell differentiations utilizing Papanicolaou staining techniques. The advantages of the Aerospray Cytology Slide Stainer/Cytocentrifuge is that the device performs two functions of sample preparation through cytocentrifugation and sample staining. The system maximizes cell recovery to the slide through the use of its Cytopro® Rotor, eliminates cross-contamination with an application of fresh stain for each slide, and provides programmable regressive and progressive staining capabilities that can be stored in memory to meet the needs and preferences of any end user. The instrument standardizes staining across multiple labs, provides consistently high-quality control, is low maintenance, reduces the labor/cost per slide, enables laboratory compliance, and is the perfect back-up for high automation laboratories for specialty staining and during maintenance. “ELITechGroup’s portfolio of Aerospray slide stainers and cytocentrifuges has enabled the company to develop a worldwide reputation for performance and reliability. Our new Aerospray Cytology Stainer/Cytocentrifuge proves our commitment to ongoing innovation by expanding into new laboratories where we can offer superior staining results,” says Bryce McEuen, Vice President, Biomedical Systems. ELITechGroup will be showcasing the Aerospray Cytology Slide Stainer/Cytocentrifuge at key industry events throughout the year of 2020. Learn more at AerosprayStaining.com.
About ELITechGroup
ELITechGroup is a privately held group of worldwide manufacturers and distributors of in vitro diagnostic equipment and reagents for clinical systems, microbiology, molecular diagnostics, hematology, cytology, and sweat test systems. Their mission is to improve patient care by empowering laboratories to do more in less time, with accuracy, to enable rapid and accurate course of treatment for patients.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/PRODUCT_CLI_ELITECHGROUP.jpg 286 638 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:38ELITechGroup’s Staining Technology Expands with Aerospray® Cytology Slide Stainer/Cytocentrifuge

GE Healthcare Life Sciences releases software for cell therapy workflow

, 26 August 2020/in Product News /by 3wmedia

GE Healthcare Life Sciences continues to build out its flexible solutions across the cell therapy workflow with the commercial availability of SpinOculation C-Pro Protocol Software. Part of the Sepax™ C-Pro Cell Processing System, the software closes and automates the cell transduction step. When used in combination with the Sepax C-Pro instrument and CT-60.1 single-use kit, the software enables users to choose the volume and cell concentration from initial cell preparation through transduction to final resuspension, without compromising cell viability and virus stability.
Catarina Flyborg, General Manager, Cell and Gene Therapy, GE Healthcare Life Sciences, said: “Cell therapy manufacturing is complex and requires advanced technologies.
The SpinOculation C-Pro software application automates and simplifies a critical step in the cell therapy workflow and helps accelerate the development of next generation therapeutics.” Additionally, the SpinOculation C-Pro Protocol helps users:

  • Gain reproducibility in transduction steps with an automated and closed solution
  • Save time in the manufacturing process by reducing manipulations
  • Optimize transduction performance by adjusting open system parameters
  • Simplify process validation by not using transduction enhancers

The SpinOculation C-Pro application software is available worldwide.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 0 0 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:39GE Healthcare Life Sciences releases software for cell therapy workflow
CLI TRIMERO EPN on July 4 2019

C1q, C1 Inhibitor, C5 and Factor B assays for nephelometry and turbidimetry

, 26 August 2020/in Product News /by 3wmedia

TRIMERO offers C1q, C5, C1 (Esterase) Inhibitor and Factor B (C3 Proactivator) CE- marked assays for nephelometry and turbidimetry.
Assays are available for IMMAGE® immunochemical systems of Beckman Coulter and for BN™ Series nephelometers of Siemens Healthineers.
Turbidimetric assays and applications are also available for the most popular clinical chemistry analysers.
In order to ensure lot to lot traceability, values ​​have been referred to the International Ref. Preparation for human serum complement Factors (NIBSC code: W1032) of the WHO (World Health Organization). 
Other available assays for nephelometry and turbidimetry include:
KLoneus® Free Light Chains (FLC), Serum Amyloid A (SAA), IgD Immunoglobulins, Retinol Binding Protein (RBP) for serum and urine, Soluble Transferrin Receptor (sTfR), Hemopexin, Cystatin-C for serum and urine, A1-Microglobulin, B2-Microglobulin for serum and urine, Kappa and Lambda Light Chains for serum and urine.
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/CLI_TRIMERO_EPN_on_July_4__2019.png 353 402 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:49C1q, C1 Inhibitor, C5 and Factor B assays for nephelometry and turbidimetry
horizon discovery

Horizon Discovery extends coverage of OncoSpan reference standards to FFPE and Liquid Biopsy

, 26 August 2020/in Product News /by 3wmedia

Horizon Discovery Group, a global leader in the application of gene editing and gene modulation for cell line engineering, has added two new sample formats to its cell-based OncoSpan reference standards for use in the development and validation of workflows for cancer diagnostic assays.
Horizon’s OncoSpan range now includes formalin-fixed, paraffin-embedded (FFPE) and cell-free DNA (cfDNA) formats for mimicking solid tumors and liquid biopsy samples, respectively, in addition to its well-established genomic DNA (gDNA) format. Its cfDNA format offers one of the largest number of variants and genes, over 380 and 152 respectively, of any characterized reference standard to help standardize liquid biopsy testing.
These cell-line derived reference standards closely mimic patient samples and offer an unlimited and reproducible resource to help ensure consistency during the establishment and validation of diagnostic assays. All three formats are delivered with batch-specific, next-generation sequencing (NGS) data, orthogonally validated by ddPCR, to allow researchers to further validate their analysis pipeline.
For further information, visit: horizondiscovery.com/en/products/diagnostic-reference-standards/PIFs/OncoSpan-cfDNA
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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/horizon_discovery-scaled.jpg 2560 2560 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:34Horizon Discovery extends coverage of OncoSpan reference standards to FFPE and Liquid Biopsy
logo integra biosciences

Pipette tips designed for Integra pipettes

, 26 August 2020/in Product News /by 3wmedia

INTEGRA Biosciences has developed its GripTip pipette tips range to overcome the problems associated with the use of universal pipette tips. Universal pipette tips require hammering on to stretch the tip, often resulting in a suboptimal fit that can lead to loose, leaking and falling off tips. GripTips are designed to offer a perfect fit on INTEGRA pipettes, effortlessly snapping onto the tip fittings with low attachment and ejection forces. This ensures that all tips are at the same height, guaranteeing perfect alignment and seal, even when performing side well touch-offs. They span a wide volume range – from 0.5 to 5000 µl – and are available in sterile,  non-sterile and filtered options. The portfolio also includes a number of specialty GripTips, such as low retention tips for recovering viscous solutions, wide bore tips for cellular applications, short tips for improved ergonomics and targeting of small wells, and extra long tips for improved access to tubes. This range is continuously being expanded to ensure that there are GripTips to meet the needs of every customer, for every application. The two latest tips include a 1250 µl short tip – perfect for ergonomically pipet-ting large volumes, by eliminating the need to hold the pipette high over the bench, reducing the risk of RSI – and a 300-µl long tip that, at 102 mm long, enables the user to easily reach the bottom of standard 100 ml tubes. To aid tip selection, INTEGRA has launched its GripTip selector, simply using filters to identify the most suitable tips for the required workflow in seconds.

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https://clinlabint.com/wp-content/uploads/sites/2/2020/08/logo-integra_biosciences.jpg 170 600 3wmedia https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png 3wmedia2020-08-26 09:16:522021-01-08 11:20:44Pipette tips designed for Integra pipettes
C432 Abbott Alinity m

Infectious disease testing system and assays

, 26 August 2020/in Product News /by 3wmedia

Abbott has announced CE Mark for the Alinity m diagnostic system and assays that will allow laboratories to meet the growing demand for infectious disease testing by offering increased efficiency, speed and accuracy. This new technology will provide high flexibility in molecular diagnostic testing, allowing more tests to be done in shorter timeframes, while reducing the space and number of instruments needed to conduct large amounts of tests. The World Health Organization (WHO) reports that more than a billion people around the world are living with infectious diseases. For people living with infectious diseases, quick and accurate molecular test results are needed to help prevent the spread of communicable diseases globally. Advanced molecular testing also allows patients to be diagnosed correctly and then monitored for their response to treatment. Molecular laboratories are playing an increasingly important role in providing critical test results for infectious disease diagnosis. Alinity m will significantly improve the way these laboratories operate by letting staff run any sample at any time, without the need to group samples, allowing them to focus on giving physicians the information they need to make accurate, timely clinical decisions. Alinity m provides superior flexibility for lab staff and faster testing results for clinicians and patients.  Alinity m may also reduce the lab equipment footprint from four to six instruments down to one – decreasing the space requirements and hours spent learning and maintaining different instruments. Now available in countries that recognize CE Mark, Alinity m offers initial assays including virologic testing for human immunodeficiency virus type 1 (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV); sexual health-related testing for Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, and Mycoplasma genitalium or CT/NG/TV/MG panel; and high-risk human papillomavirus (HPV) testing. Local product availability may vary depending on geographic location.

ABBOTT
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