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Rapid supercritical fluid chromatography–tandem mass spectrometry (SFC-MS/MS) for the routine quantification of retinol and α-tocopherol in human serum and plasma

As interest in vitamins A and E has increased in recent years, so too has the need for rapid and reliable methods by which these compounds can be assayed. The development of a supercritical fluid chromatography–tandem mass spectrometry (SFC-MS/MS)-based method with an automated extraction procedure provides faster analysis than other chromatographic-based methods and improved specificity.