A new genomic test for prostate cancer can help predict whether men are more likely to harbour an aggressive form of the disease, according to a new UC San Francisco study. The test, which improves risk assessment when patients are first diagnosed, can also aid in determining which men are suitable for active surveillance – […]
In the summer of 1968, a new strain of influenza appeared in Hong Kong. This strain, known as H3N2, spread around the globe and eventually killed an estimated 1 million people. A new study from MIT reveals that there are many strains of H3N2 circulating in birds and pigs that are genetically similar to the […]
A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today. The discovery of these genetic variations—chromosomal ‘typos,’ so to speak—could ultimately help researchers better understand which men are at high risk […]
Scientists at Washington University School of Medicine in St. Louis have helped identify many of the biomarkers for Alzheimer’s disease that could potentially predict which patients will develop the disorder later in life. Now, studying spinal fluid samples and health data from 201 research participants at the Charles F. and Joanne Knight Alzheimer’s Disease Research […]
The Journal of the American Heart Association published results from a study directed by Dr. Éric Thorin of the Montreal Heart Institute (MHI), which suggests for the first time that a blood protein contributes to the early development of atherosclerosis. Dr. Thorin, his team and his collaborators discovered that the blood levels of angiopoietin-like protein […]
Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and Caucasian populations. The gene is involved in the growth and development of the spine during childhood. AIS is the most common pediatric skeletal disease, affecting approximately […]
Researchers from the Masonic Cancer Center, University of Minnesota, and the University’s Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumours (MPNST) that allow them to discover new genes and gene pathways driving this type of cancer. Utilising the Sleeping Beauty transposon method, researchers in the lab of David […]
Researchers at the UCL Institute of Neurology together with international collaborators have identified a new gene, BICD2, which causes both dominant Congenital Spinal Muscular Atrophy and Hereditary Spastic Paraparesis. The team was led by Professor Mary Reilly. Dominant Congenital Spinal Muscular Atrophy is a disorder of developing anterior horn cells and is characterised by lower […]
Using the Department of Defense Serum Repository (DoDSR), University of Cincinnati researchers have identified a number of biomarkers for inflammatory bowel disease (IBD), which could help with earlier diagnosis and intervention in those who have not yet shown symptoms. The DoDSR is a biological repository operated by the U.S. Department of Defense and contains over […]
In a new study, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumour growth. Scientists call this Jekyll-and-Hyde molecule NF-kappa B. In healthy cells, it is a powerful ‘first responder,’ a vital part of the body’s immune and inflammatory responses. It […]
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