Determining whether a patient’s lung cancer has spread to nearby lymph nodes is critical for identifying the most effective therapy, but it usually requires surgery. A new study suggests, however, that measuring levels of a particular molecule in a sample of tumour tissue might accurately answer the question. Researchers at The Ohio State University Comprehensive […]
The human papillomavirus (HPV) may be to blame for the alarming increase of young adults with oropharyngeal cancer, according to researchers from Henry Ford Hospital in Detroit. The study reveals an overall 60 percent increase from 1973 and 2009 in cancers of the base of tongue, tonsils, soft palate and pharynx in people younger than […]
Massachusetts General Hospital (MGH) researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer’s disease (AD) that strikes after the age of 60. The two mutations occur in a gene called ADAM10 – coding for an enzyme involved in processing the amyloid precursor protein – which now […]
Using powerful genetic sequencing technology, a team of investigators, led by researchers at the Icahn School of Medicine at Mount Sinai, scanned the genome of hundreds of individuals, and discovered those diagnosed with autism spectrum disorder (ASD) were more likely to have gene deletions than were people without the disorder. That means those individuals — […]
For the first time, researchers have created a model that could help unlock what causes adenomyosis, a common gynaecological disease that is a major contributor to women having to undergo hysterectomies. In a two-step process, a team led by Michigan State University’s Jae-Wook Jeong first identified a protein known as beta-catenin that may play a […]
Using mice, lab-grown cells and clues from a related disorder, Johns Hopkins researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in the way certain cells communicate with their structural scaffolding. They say the new insights point the way toward potentially developing drugs for the […]
An international team of scientists—including researchers at GENYO, the Centre for Genomics and Oncological Research (Pfizer-University of Granada- Andalusian Regional Government)—has described a molecular mechanism that facilitates the defence of the human genome against ‘bombarding’ by mobile DNA sequences. Abnormalities in the mechanism could be responsible for some symptoms of DiGeorge syndrome, a rare disease. […]
Huskies football defensive lineman Caleb Eidsvik takes up a lot of room as he sits on an examining table in the Huskies trainer’s room at Griffiths Field, patiently waiting for pharmacology student Hungbo Qudus to draw a small sample of his blood. At six-foot three and 260 pounds, Eidsvik exudes strength and good health. And […]
Life-threatening blood clots can form in anyone who sits on a plane for a long time, is confined to bed while recovering from surgery, or takes certain medications. There is no fast and easy way to diagnose these clots, which often remain undetected until they break free and cause a stroke or heart attack. However, […]
A Chinese research team composed of Shenzhen Second People’s Hospital, BGI and other institutes reports their latest study on bladder cancer genomics. The discoveries were made using whole-genome and exome sequencing technologies and provide evidence that genetic alterations affecting the sister chromatid cohesion and segregation (SCCS) process may be involved in bladder tumorigenesis and open […]
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