For the first time, scientists at King’s College London have identified a gene linking the thickness of the grey matter in the brain to intelligence. The study may help scientists understand biological mechanisms behind some forms of intellectual impairment. The researchers looked at the cerebral cortex, the outermost layer of the human brain. It is […]
Findings show how a genetic mutation in untreated patients is linked to aggressive cancer later in life. It was previously thought that the mutation only occurred in response to therapy. The research highlights why relapses could occur in some men following hormone therapy. And it could help identify those patients that will develop fatal prostate […]
Cancer researchers led by stem cell scientist Dr. John Dick have discovered a pre-leukemic stem cell that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukaemia (AML). The research is a significant leap in understanding the steps that a normal […]
Researchers at the Indiana University School of Medicine have discovered a highly accurate, non-invasive test to identify benign pancreatic cysts, which could spare patients years of nerve-racking trips to the doctor or potentially dangerous surgery. The test, which analyses fluid from pancreatic cysts, can identify a common type of benign cyst that can’t be differentiated […]
Researchers have developed a novel technique for detecting ALK rearrangements in non-small cell lung cancers (NSCLCs) that is more sensitive and easier to perform than currently available techniques. The technique can help enhance the routine practice of diagnostic ALK testing on NSCLCs, which is crucial for identifying patients with advanced NSCLC who are most likely […]
Cancer rates in developing nations have climbed sharply in recent years, and now account for 70 percent of cancer mortality worldwide. Early detection has been proven to improve outcomes, but screening approaches such as mammograms and colonoscopy, used in the developed world, are too costly to be implemented in settings with little medical infrastructure. To […]
Cancer cells have long been known to have higher rates of the energy-generating metabolic pathway known as glycolysis. This enhanced glycolysis, a phenomenon known as the Warburg effect, is thought to allow cancer cells to survive the oxygen-deficient conditions they experience in the centre of solid tumours. A study reveals how damaged cells normally switch […]
The Icahn School of Medicine at Mount Sinai announced the launch of a more accurate carrier screening test for spinal muscular atrophy (SMA), one of the most common and severe autosomal recessive disorders. This new test will help prospective parents more effectively identify whether they carry the mutation that will affect their offspring. The test […]
An antibody found in the blood of people with multiple sclerosis (MS) may be present long before the onset of the disease and its symptoms, according to a study. ‘If our results can be replicated in larger populations, our findings may help to detect MS earlier in a subgroup of patients,’ said study author Viola […]
An international team led by researchers at the Broad Institute and Massachusetts General Hospital (MGH) has identified mutations in a gene that can reduce the risk of developing type 2 diabetes, even in people who have risk factors such as obesity and old age. The results focus the search for developing novel therapeutic strategies for […]
November 2024
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