Researchers at Karolinska Institutet in Sweden have for the first time identified a gene driving the development of pernicious adipose tissue in humans. The findings imply that the gene may constitute a risk factor promoting the development of insulin resistance and type 2 diabetes. Adipose tissue can expand in two ways: by increasing the size […]
A new theory about disorders that attack the brain and spinal column has received a significant boost from scientists at Washington University School of Medicine in St. Louis. The theory attributes these disorders to proteins that act like prions, which are copies of a normal protein that have been corrupted in ways that cause diseases. […]
New research from the University of Rochester Medical Center describes how exposure to air pollution early in life produces harmful changes in the brains of mice, including an enlargement of part of the brain that is seen in humans who have autism and schizophrenia. As in autism and schizophrenia, the changes occurred predominately in males. […]
Improved diagnosis and management of one of the most common cancers in men – prostate cancer – could result from research at the University of Adelaide, which has discovered that seminal fluid (semen) contains biomarkers for the disease. Results of a study have shown that the presence of certain molecules in seminal fluid indicates not […]
Scientists have identified four biomarkers that may help resolve the difficult differential diagnosis between malignant pleural mesothelioma (MPM) and non-cancerous pleural tissue with reactive mesothelial proliferations (RMPs). This is a frequent differential diagnostic problem in pleural biopsy samples taken from patients with clinical suspicion of MPM. The ability to make more accurate diagnoses earlier may […]
Hakon Hakonarson, MD, PhDA large new analysis of DNA from thousands of patients has uncovered several underlying gene networks with potentially important roles in autism. These networks may offer attractive targets for developing new autism drugs or repurposing existing drugs that act on components of the networks. Furthermore, one of the autism-related gene pathways also […]
In a new study, scientists at the National Institutes of Health took a molecular-level journey into microtubules, the hollow cylinders inside brain cells that act as skeletons and internal highways. They watched how a protein called tubulin acetyltransferase (TAT) labels the inside of microtubules. The results answer long-standing questions about how TAT tagging works and […]
A new Moffitt Cancer Center study shows that counselling from a genetic health care provider before genetic testing educates patients and may help reduce unnecessary procedures. Up to 10 percent of cancers are inherited, meaning a person was born with an abnormal gene that increases their risk for cancer. ‘Pre-test genetic counselling in which a […]
This spring has brought rare but tangible moments of progress against the devastating lung disease idiopathic pulmonary fibrosis (IPF), which afflicts millions of people worldwide. Two drugs recently showed promise in clinical trials, and now a study offers both an unprecedentedly deep explanation of how the disease progresses and introduces another potential therapeutic avenue. The […]
An imbalance of female sex hormones among men in Western nations may be contributing to high levels of male obesity, according to new research from the University of Adelaide. In a paper researchers from the University’s School of Medical Sciences suggest that obesity among Western men could be linked with exposure to substances containing the […]
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