Scientists have identified a crucial molecular key to healthy embryo implantation and pregnancy in a study that may offer new clues about the medical challenges of infertility/subfertility, abnormal placentation, and placenta previa. Multi-institutional teams conducted the study and was led by researchers at Cincinnati Children’s Hospital Medical Center. The authors found that uterine expression of […]
Dysfunction in dopamine signalling profoundly changes the activity level of about 2,000 genes in the brain’s prefrontal cortex and may be an underlying cause of certain complex neuropsychiatric disorders, such as schizophrenia, according to UC Irvine scientists. This epigenetic alteration of gene activity in brain cells that receive this neurotransmitter showed for the first time […]
The age at which girls reach sexual maturity is influenced by ‘imprinted’ genes, a small sub-set of genes whose activity differs depending on which parent passes on that gene, according to new research. The findings come from an international study of more than 180,000 women involving scientists from 166 institutions worldwide, including the University of […]
Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches, researchers funded by the National Institutes of Health have found. Heritability also outweighed other risk factors in this largest study of its kind to date. About 52 percent of […]
A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found. The research potentially could lead to new therapies to treat obesity and diabetes, since the transcription factor involved – spliced X-box binding protein 1 […]
The routine use of a molecular testing panel developed at UPMC greatly increases the likelihood of performing the correct initial surgery for patients with thyroid nodules and cancer, report researchers from the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter. The test improved the chances of patients getting the correct initial surgery by […]
A genetic screening test may help predict which patients with one of the most common childhood kidney diseases will respond to standard therapies. Using this test could help guide clinicians as they counsel and treat patients. Sporadic nephrotic syndrome is one of the most common kidney diseases in children, and it can have a genetic […]
It has been some time in the making, but the newly designed Greiner Bio-One website was finally launched at the beginning of July along with our newly designed webshop. Product and order information for the business divisions Preanalytics (specimen collection), BioScience (products for the biotech industry), Diagnostics (DNA arrays) and OEM (customised developments for the […]
A study led by Yale Cancer Center may provide clues to how some aggressive cancers turn off, or silence, genes critical to suppressing tumours. The findings suggest that this gene silencing process could be interrupted to increase the chances that aggressive tumours will respond to treatment. As cancer develops, it often outstrips its blood supply […]
Understanding eye diseases is tricky enough. Knowing what causes them at the molecular level is even more confounding. Now, University of Iowa researchers have created the most detailed map to date of a region of the human eye long associated with blinding diseases, such as age-related macular degeneration. The high-resolution molecular map catalogues thousands of […]
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