A novel study by the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) found that an increase in a gene known as Leo1 affects other genes that are directly implicated in acute myelogenous leukaemia (AML), increasing the incidence of cancer. Led by Associate Professor Chng Wee Joo, Deputy Director […]
University of Adelaide psychiatry researchers have developed a model that could help to predict a patient’s likelihood of a good outcome from treatment – from their very first psychotic episode. The model is based on a range of factors, including clinical symptoms, cognitive abilities, MRI scans of the brain’s structure, and biomarkers in the patient’s […]
Scientists at IRB Barcelona in collaboration with researchers at the University of Barcelona observe that aggregates of 20 to 100 units of beta-amyloid have a structure that is the most harmful to neurons. This is the first time that a method allows scientists to monitor aggregation while simultaneously detect a structural pattern responsible for the […]
Scientists at IRB Barcelona have observed that, when deprived of food, flies that do not express p53 show poor management of energy store. The study further supports the involvement of this molecule—traditionally associated with tumour suppression—in metabolism. The researchers provide new insights to study p53 function in metabolic diseases such as diabetes and obesity. Most […]
A new genetic finding from Duke Medicine suggests that some people who are prone to hostility, anxiety and depression might also be hard-wired to gain weight when exposed to chronic stress, leading to diabetes and heart disease. An estimated 13 percent of people, all of whom are Caucasian, might carry the genetic susceptibility, and knowing […]
The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly. Scientists at the University of Michigan and the U-M Health System recently discovered a protein mutation that causes the devastating disease dyskeratosis congenita, […]
The ability to distinguish between odours declines steadily with age, and age-related smell loss can have a substantial impact on lifestyle and wellbeing for the elderly. “Smells impact how foods taste. Many people with smell deficits lose the joy of eating. They make poor food choices, get less nutrition. They can’t tell when foods have […]
Researchers at UT Southwestern Medical Center have found an “Achilles heel” in a metabolic pathway crucial to stopping the growth of lung cancer cells. At the heart of this pathway lies PPARγ (peroxisome proliferation-activated receptor gamma), a protein that regulates glucose and lipid metabolism in normal cells. Researchers demonstrated that by activating PPARγ with antidiabetic […]
Researchers at the University of California, San Diego School of Medicine have, for the first time, clearly defined the epidemiology of gastrointestinal stromal tumours (GIST), which occur primarily in the lining of the stomach and small intestine. One key finding: Patients of Asian descent, who have not previously been identified as an at-risk population, are […]
Scientists have been labouring to detect cancer and a host of other diseases in people using promising new biomarkers called “exosomes.” Indeed, Popular Science magazine named exosome-based cancer diagnostics one of the 20 breakthroughs that will shape the world this year. Exosomes could lead to less invasive, earlier detection of cancer, and sharply boost patients’ […]
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