Some children are more sensitive to their environments, for better and for worse. Now Duke University researchers have identified a gene variant that may serve as a marker for these children, who are among society’s most vulnerable. “The findings are a step toward understanding the biology of what makes a child particularly sensitive to positive […]
Researchers at UT Southwestern Medical Center have identified hyaluronon (HA) as a critical substance made by the body that protects against premature births caused by infection. Pre-term birth from infection is the leading cause of infant mortality in many countries according to the World Health Organization. The findings of the study are the first to […]
The discovery of new genetic mutations associated with childhood blindness, achieved through a collaboration between teams led by Michel Cayouette at the IRCM, Robert K. Koenekoop at McGill University and Doris Kretzschmar at Oregon Health and Science University has recently been published. The researchers identified a novel link between retinal degeneration and lipid metabolism. Results […]
Genetic mutations may link smoking and alcohol consumption to destruction of the pancreas observed in chronic pancreatitis, according to a 12-year study led by researchers at the University of Pittsburgh School of Medicine. The findings provides insight into why some people develop this painful and debilitating inflammatory condition while most heavy smokers or drinkers do […]
Partnering with head and neck surgeons, pathologists at Dartmouth Hitchcock Medical Center’s Norris Cotton Cancer Center developed a new use for an old test to determine if a patient’s cancer is recurring, or if the biopsy shows benign inflammation of mucosal tissues. Lead author Candice C. Black, DO explains how her team confirmed the utility […]
A new study identifies a gene that is especially active in aggressive subtypes of breast cancer. The research suggests that an overactive BCL11A gene drives triple-negative breast cancer development and progression. The research, which was done in human cells and in mice, provides new routes to explore targeted treatments for this aggressive tumour type. There […]
An exhaustive hereditary analysis of a large Louisiana family with vision issues has uncovered a new gene tied to an incurable eye disorder called retinitis pigmentosa, according to an examination led by scientists at The University of Texas Health Science Center at Houston (UTHealth). It is a family of eye diseases that affects millions worldwide. […]
Despite a strong suspected link between genetics and asthma, commonly found genetic mutations account for only a small part of the risk for developing the disease — a problem known as missing heritability. Rare and low frequency genetic mutations have been thought to explain missing heritability, but it appears they are unlikely to play a […]
For some children with autism, the ‘Tooth Fairy’ lives in San Diego and wears a white coat. And the Tooth Fairy may offer an answer to what causes their autism, without painful blood draws or skin biopsies. Alysson Muotri, associate professor of paediatrics and cellular molecular medicine at the University of California, San Diego, created […]
The largest genome-wide association study to date of the malaria parasite Plasmodium falciparum unveils a complex genetic architecture that enables the parasite to develop resistance to our most effective antimalarial drug, artemisinin. The results could help to improve early detection of emerging artemisinin resistance. The global research collaboration analysed 1612 samples from 15 locations in […]
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