The field of medical genetics is swiftly evolving. It’s a period of rapid scientific discovery, new technologies and subsequent translation into medical practice, public policy and public health. But what role should the Medical Genetics specialist have since genetics impacts all patients and specialties in some way? In an effort to clearly define the changing […]
A ‘pill on a string’ developed by researchers at the University of Cambridge could help doctors detect oesophageal cancer – cancer of the gullet – at an early stage, helping them overcome the problem of wide variation between biopsies, suggests research. The ‘Cytosponge’ sits within a pill which, when swallowed, dissolves to reveal a sponge […]
A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, researchers at the BCI have shown. The discovery could lead to a non-invasive, inexpensive test to screen people at high risk of developing the disease. Dr Tatjana Crnogorac-Jurcevic’s group has shown that the three-protein ‘signature’ can both identify […]
Scientists at the University of British Columbia have discovered a gene that could be an important cause of obesity. The gene, which encodes a protein called 14-3-3zeta, is found in every cell of the body. But when scientists silenced the gene in mice, it resulted in a 50 per cent reduction in the amount of […]
Research led by Maria Clara Franco of the Burnett School of Biomedical Sciences has implications for the treatment of cancer and neurodegenerative diseases. New research from the University of Central Florida has shed light on the workings of a particular protein found in the human body that could have future implications for the treatment of […]
After generating new brain tumour models, Cedars-Sinai scientists in the Board of Governors Regenerative Medicine Institute identified the role of a family of genes underlying tumour growth in a wide spectrum of high grade brain tumours. ‘With these new genetic findings, our group of researchers plan to develop targeted therapeutics that we hope will one […]
A new test developed by UBC researchers allows physicians to measure the effects of gene silencing therapy in Huntington’s disease and will support the first human clinical trial of a drug that targets the genetic cause of the disease. The gene silencing therapy being tested by UBC researchers aims to reduce the levels of a […]
Scientists have identified a new biomarker in the blood that could help identify more women at an increased risk of breast cancer. Such women might benefit from risk-reducing measures. In a prospective study, researchers from Imperial College London and the Human Genetics Foundation (HuGeF) in Torino, Italy, have concluded that DNA methylation levels in blood […]
Scientists who analysed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets for treating many of these diseases, in some cases with existing drugs already available for non-autoimmune disorders. Autoimmune diseases, such as […]
Virginia Tech researchers have identified a biomarker in pre-diabetic individuals that could help prevent them from developing Type II diabetes. The researchers discovered that pre-diabetic people who were considered to be insulin resistant — unable to respond to the hormone insulin effectively — also had altered mitochondrial DNA. Researchers made the connection by analysing blood […]
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