People with high levels of good cholesterol, or high-density lipoprotein, are not as safe from heart disease when high levels of a newly identified biomarker of inflammation in the arteries are also found in their bloodstream, according to a new study. In the study of nearly 3,000 patients, researchers from the Intermountain Medical Center Heart […]
Skin cancer is the most common of all cancers, and melanoma, which accounts for 2% of skin cancer cases, is responsible for nearly all skin cancer deaths. Melanoma rates in the U.S. have been rising rapidly over the last 30 years, and although scientists have managed to identify key risk factors, melanoma’s modus operandi has […]
Researchers have identified a new set of genes that may be responsible for the two most common and disabling neurological conditions, stroke and dementia. The study may help researchers better understand, treat and prevent ischemic and haemorrhagic stroke, and perhaps Alzheimer’s disease and other dementias. Stroke is the leading neurological cause of death and disability […]
The human heart is a remarkable muscle, beating more than 2 billion times over the average life span. But the heart’s efficiency can decrease over time. One major contributor to this decreased function is cardiac hypertrophy – a thickening of the heart muscle, resulting in a decrease in the size of the left and right […]
The occurrence of chemotherapy resistance is one of the major reasons for failure in cancer treatment. A study led by Óscar Fernández-Capetillo, Head of the Genomic Instability Group at the Spanish National Cancer Research Centre (CNIO), has identified a new determinant of chemotherapy resistance. In this regard, they employed ATR kinase inhibitors, which were previously […]
Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley. This intolerance leads to an inflammatory reaction in the small intestine that hampers the absorption of nutrients. The only treatment is a strict, life-long, gluten-free diet. It has been known for some time that […]
Newcastle scientists and medics have developed a new type of genetic blood test that diagnoses scarring in the liver – even before someone may feel ill. It is the first time an epigenetic signature in blood has been discovered which is diagnostic of the severity of fibrosis for people with Non-alcoholic Fatty Liver Disease (NAFLD). […]
The babies of obese women who develop gestational diabetes are five times as likely to be excessively large by six months of pregnancy, according to new research led by the University of Cambridge. The study, which shows that excessive foetal growth begins weeks before at-risk women are screened for gestational diabetes, suggests that current screening […]
While research has identified hundreds of genes required for normal memory formation, genes that suppress memory are of special interest because they offer insights into how the brain prioritizes and manages all of the information, including memories, that it takes in every day. These genes also provide clues for how scientists might develop new treatments […]
Genomic makeup of colorectal cancers predicts immune system ability to fight tumours Colorectal cancers heavily bedecked with tumour-related proteins called neoantigens are likely to be permeated with disease-fighting white blood cells, researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard report in a new study. Because such an influx of white […]
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