Author Archive for: 3wmedia

Children diagnosed with autism spectrum disorder (ASD) have greater numbers of harmful mutations in their mitochondrial DNA than family members, report Zhenglong Gu of Cornell University in Ithaca, New York, and colleagues, in a study. Increasingly, studies point to malfunctions in mitochondria — the powerhouses of the cell — as a cause of autism spectrum […]

Some people adapt easily to shift work, but not everyone can handle constant disruptions to their daily rhythm. Finnish researchers have now found that a melatonin receptor gene influences tolerance to shift work.The new study is the first time the genetic factors underlying poor tolerance to shift work were systematically examined. Covering the entire genome, […]

Alzheimer’s disease is characterized by two types of cerebral lesion: amyloid plaques and neurofibrillary tangles. Amyloid beta peptide (Aβ), naturally present in the brain, builds up over the years as a result of genetic and environmental factors until it forms amyloid plaques. This build-up is toxic for nerve cells: it leads to a loss of […]

A new bioinformatic framework developed by researchers at University of California San Diego School of Medicine has identified key proteins significantly altered at the gene-expression level in biopsied tissue from patients with diabetic kidney disease, a result that may reveal new therapeutic targets. In a recently published paper, researchers, led by Kumar Sharma, MD, professor […]

Researchers have identified a new pathway and with it a protein, BRD4, necessary for breast cancer cells to spread. The findings may provide a new target to suppress breast cancer metastasis. Triple-negative breast cancer is considered the worst subgroup of breast cancer. It is highly aggressive and responds poorly to the current therapeutic tools resulting […]