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Author Archive for: 3wmedia
Entries by 3wmedia
Tumour markers: why not VOCs?
Since early diagnosis of cancer is crucial in reducing mortality, much research is directed towards finding minimally invasive methods of detecting early tumour growth. In 1971 the Nobel Prize winner Linus Pauling froze his exhaled breath to analyse the volatile organic compounds (VOCs) it contained by gas chromatography. Forty-six years later, although many studies have […]
The promise and the challenges
There is growing interest in tumour markers as aids for the diagnosis, staging and management of cancer. Some are expected to succeed, after several years of evaluation to trials and eventual clinical use. A large number, however, are not likely to make it beyond development. On their part, physicians need to be aware of both […]
Circulating peptidomics: a promising approach for the diagnosis and treatment of human cancers
Recently, low-molecular-weight-peptide enrichment from blood samples by on-chip fractionation with nanopore platforms has been established successfully for the quantification and phenotypic characterization of the substrate degradome – the peptide products generated by the protease activity of a tumour environment. This article will provide evidence for this peptidomics-based approach and the clinical relevance in future therapeutic […]