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Author Archive for: panglobal
Entries by panglobal
Insight into advances in diagnosis of Barrett’s esophagus
Barrett’s esophagus has been established as a pre-cancerous condition that increases an individual’s risk of developing esophageal cancer, and so regular monitoring people with Barrett’s esophagus can help improve the survival rates of those who develop cancer. However, diagnosis is usually by endoscopy, which is invasive, unpleasant and resource-intensive. CLI caught up with Charlene Tang […]
Gastrointestinal Disorders: Literature Review
Thiopurine pharmacogenomics and pregnancy in inflammatory bowel disease Andoh A, Kawahara M, Imai T, et al. J Gastroenterol 2021; 56(10): 881–890 The thiopurine drugs azathioprine and 6-mercaptopurine are widely used for the maintenance of clinical remission in steroid-dependent inflammatory bowel disease (IBD). Thiopurines are recommended to be continued throughout pregnancy in IBD patients, but conclusive […]
Therapeutic drug monitoring of favipiravir, a potential COVID-19 drug candidate
The COVID-19 outbreak caused by severe acute respiratory syndrome virus 2 (SARS-CoV-2) that was declared a pandemic in March 2020 has resulted in a the development of diagnostic tests and vaccines at an unprecedented speed. The development of de novo therapeutics, though, takes considerably longer, which is where the repurposing of existing drugs is being […]
How the COVID-19 response was informed by – and informs – our battle against other global health crises
The COVID-19 pandemic has reinforced the critical importance of diagnosis and access to these services, both at the individual and at a population level. The pandemic has also impacted the delivery of diagnostics and care for other medical conditions, such as HIV/AIDS, but similarly, lessons learned with COVID-19 can also be applied to improve diagnostic […]
Colorimetric histology: benefits, opportunities and future directions
Despite rapid advances in the areas of genomics and digital image analysis, cancer diagnosis remains largely reliant on tissue/cellular morphological assessment by an expert pathologist. Here, we summarize a newly developed approach to histology, based on a plasmon-induced colour change which provides instant, label-free visualization (or contrast) of cancer cells, distinguishing them from other cells […]
Researchers sound warning on vitamin B12 deficiency for people following plant-based diets
Leading researchers are warning of the dangers of a quiet epidemic of vitamin B12 deficiency in people who follow increasingly popular plant-based diets and explain how it can be addressed.