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Computational design reveals structural principles governing membrane protein stability

29 October 2025 in Featured Articles /by panglobal

Scientists at Scripps Research have developed a computational approach for designing synthetic membrane proteins, uncovering critical atomiclevel interactions that govern protein folding and stability within cellular lipid environments. The methodology offers new insights into disease-related protein dysfunction and potential therapeutic targets. Membrane proteins constitute essential molecular machinery for cellular function, mediating substance transport, signal transmission, […]

Tyramide signal amplification allows analysis of single circulating tumour cells and extracellular vesicles from glioblastoma liquid biopsies

29 October 2025 in Featured Articles, Tumour Markers /by panglobal

Background What are circulating tumour cells and extracellular vesicles? Circulating tumour cells (CTCs) are cancer cells that have been shed from a primary tumour into the bloodstream or lymphatic system. They are carried around the body and can be the seeds that form metastases. Extracellular vesicles (EVs) are tiny lipid-bilayer bound particles that are shed […]

Development of gender-specific thresholds in urine flow cytometry testing for urinary tract infection

29 October 2025 in Featured Articles, Urine Analysis /by panglobal

Background A urinary tract infection (UTI) is an infection – usually bacterial – of any part of the urinary tract. Most commonly, a UTI would involve the lower urinary tract (urethra and bladder), and non-complicated lower UTIs are more common in women. Mild UTIs can resolve naturally, and pain killers, application of heat to the […]

UTI diagnostic stewardship can improve antibiotic stewardship

29 October 2025 in Featured Articles, Urine Analysis /by panglobal

It could be easy to imagine that the gold standard for diagnosis of urinary tract infection (UTI) is urine culturing with antimicrobial susceptibility testing to ensure prescription of the correct antibiotic. However, there are many aspects to the diagnosis of a UTI and an overreliance on urine culture alone can result in asymptomatic bacteriuria being […]

Integra Biosciences launches $10.000 Future Lab Grant competition to modernise laboratory workflows

29 October 2025 in E-News /by panglobal

INTEGRA Biosciences has announced a competitive grant programme offering laboratories the opportunity to win $10,000 worth of pipetting and automation equipment to address operational challenges and enhance experimental efficiency.

Roche introduces sixth-generation troponin T test with enhanced diagnostic precision

28 October 2025 in Product News /by panglobal

Roche has unveiled results from its comprehensive TSIX Study Program evaluating a new high-sensitivity cardiac troponin T assay designed to improve acute myocardial infarction diagnosis in emergency settings. The sixth-generation test, recently granted CE Mark approval, demonstrates significant advances in sensitivity and accuracy for detecting cardiac events.

Takara Bio launches defined medium for high-yield extracellular vesicle production

28 October 2025 in Product News /by panglobal

Takara Bio Europe has introduced Cellartis® MSC EV Wonder™, a chemically defined, xeno-free culture medium designed to address scalability challenges in mesenchymal stem cell-derived extracellular vesicle (MSC-EV) manufacturing. The product targets researchers developing cell-free therapeutic candidates for regenerative medicine and immunomodulation applications.

SynGenSys unveils NK.SET synthetic promoter library for natural killer cell therapies

28 October 2025 in Product News /by panglobal

SynGenSys has introduced NK.SET™, the first commercially available synthetic promoter library designed specifically for natural killer (NK) cell immunotherapies. The Sheffield-based biotechnology company’s announce-ment marks a significant validation of its platform for engineering tissue-specific gene regulation control elements.

Bio-Rad launches consolidated specialty immunoassay quality control in Europe

28 October 2025 in Product News /by panglobal

Bio-Rad launches consolidated specialty immunoassay quality control in Europe Bio-Rad Laboratories has introduced its Specialty Immunoassay Plus (SPIA Plus) control system to European clinical laboratories, offering enhanced quality monitoring capabilities for specialty immunoassay testing procedures.

Amsbio expands CAR-T research tools with sterile cell line portfolio

28 October 2025 in Product News /by panglobal

Amsbio has launched an expanded portfolio of ready-to-use, sterile cell lines designed to accelerate CAR-T cell therapy research for leukaemia treatment. The offering addresses growing demand for standardised cellular tools following the 2017 FDA approval of CAR-T therapy for children and adolescents with B cell acute lymphoblastic leukaemia (ALL).

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