Extending standardization beyond the analytical phase
Researchers at the University of California San Diego have developed an innovative nanotechnology that can create temporary openings in the nuclear membrane of living cells without damaging the cell’s outer structure. This breakthrough, published in the journal Advanced Functional Materials [1], could revolutionize gene therapy and drug delivery methods by providing direct access to the […]
Researchers from Kindai University and collaborating institutions have achieved a significant milestone in cell biology by creating artificial cell nuclei within living mouse eggs. The study, published in the journal Genes to Cells [1], demonstrates for the first time that functional nuclei can be constructed by injecting purified DNA solution into oocytes, mimicking the fertilisation […]
In a significant advancement for neuroscience, researchers have successfully mapped nearly 140,000 neurons in the brain of a common fruit fly, creating the largest and most complete connectome of an adult animal to date. This groundbreaking work, supported by the U.S. National Institutes of Health (NIH), provides a detailed wiring diagram of the fruit fly […]
Blood gas analysis for the diagnosis of acid–base disorders is now mainly performed at the point-of-care and the results reported can be affected by a number of factors. Users should be aware of the possible pitfalls to prevent errors in diagnosis and to optimize patient management. CLI chatted to Dr Kate Shipman (Consultant Chemical Pathologist, […]
In a previous article (CLI October 2021 “Diagnosis of acute hepatic porphyria”), we discussed in detail the biochemistry and the diagnosis of the different types of porphyria. Here, we give a brief recap before going on to discuss a recent paper by Gallagher et al. that examined the effects of different specimen storage and handling […]
According to the most recent statistics provided by Cancer Research UK, lung cancer is the third most common cancer in the UK, with around 49 000 new cases in the UK every year which account for 13% of all new cancer cases.
Breast cancer is the most common cancer in females in the UK, with around 56 800 new cases diagnosed every year.
Continuous flow rate measurement for improved fraction purity and yield
New device aims to enhance efficiency in pharmaceutical research and development
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