TESTA Analytical’s Prep Flowmeter enhances preparative HPLC fraction collection accuracy
Continuous flow rate monitoring during preparative high-performance liquid chromatography (HPLC) purification has been enhanced with the introduction of a new compact device from TESTA Analytical Solutions. The Prep Flowmeter enables real-time monitoring of liquid flow rates up to 650 ml/minute, addressing key challenges in preparative-scale purification processes.
The device has particular relevance for laboratories conducting preparative chromatography for applications such as chiral drug purification, peptide and protein fingerprinting, oligonucleotide analysis, and fine chemical isolation. As fraction collection in preparative HPLC systems typically relies on volume measurement, precise flow rate monitoring becomes crucial for maintaining compound purity and optimising collection parameters.
Technical specifications and features
The system utilises a non-invasive thermal flow sensor, which allows measurement across a wide dynamic range without interfering with the process flow. This approach ensures both accuracy and sensitivity while maintaining measurement resolution. The compact unit draws power via USB connection and includes an integrated high-resolution OLED display for real-time flow rate monitoring.
Data management capabilities
A PC-based application enables continuous recording and storage of flow rate measurements. The device incorporates data buffering capabilities to prevent data loss during temporary disconnections from the monitoring computer, ensuring analytical continuity during long-term purification runs.
Quality control applications
Beyond its primary role in process optimisation, the system offers additional utility for periodic performance validation and troubleshooting of preparative liquid chromatography systems. This dual functionality makes it particularly valuable for quality control laboratories and research facilities requiring regular system verification.
The device represents a practical solution for laboratories seeking to enhance their preparative HPLC workflows through improved flow rate monitoring. Its application spans both research and production environments where precise fraction collection and process validation are essential.
For further technical specifications and information, visit: https://www.testa-analytical.com/flow-monitoring.html
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