Abselion launches His-tagged protein quantification kit
Cambridge-based life sciences technology company Abselion has expanded its Amperia assay portfolio with the launch of a His-tagged protein quantification kit and sensor strips, developed in collaboration with GenScript. The new product offers researchers a ready-to-use solution for rapid measurement of His-tagged proteins in crude and purified samples.
Electrochemical detection platform extends into recombinant protein analysis
The Tagged Protein Quantification Kit | His-tag and Tagged Protein Sensor | His-tag Quantification represent an extension of Abselion’s Amperia benchtop platform beyond antibody and AAV assays into broader recombinant protein analysis. The system uses redox electrochemical detection without optics or fluidics, enabling automated quantification of biomolecules. His-tags are widely used affinity tags that support purification and detection of recombinant proteins expressed in bacterial, insect and mammalian systems. Traditional quantification methods including ELISA, gels and spectrophotometric techniques can be time-consuming and variable, particularly when working with crude samples.
Complete kit includes pre-coated sensor strips
The new assay runs in a premix competition format within Amperia’s software-controlled workflow, quantifying His-tagged proteins directly from crude or purified samples. Each kit includes pre-coated sensor strips, assay plates, detection reagents and buffers in a complete package.
The electrochemical sensor strips are pre-coated with GenScript’s THE His Tag Monoclonal Antibodies, immobilised on the sensor surface. These high-affinity antibodies offer broad reactivity across common His-tag variants and expression systems. Incorporating the antibodies directly onto the strip reduces manual handling steps and eliminates the need for additional assay development or optimisation.
Dr Ruizhi Wang, chief executive and founder of Abselion, said: “The His-tag launch is one of the first affinity-based, electrochemical, automated kits for crude samples and marks an important step in extending Amperia into one of the most widely used areas of protein science. By combining GenScript’s trusted antibody technology with our ready-to-use design, we are giving researchers faster, more dependable ways to quantify His-tagged proteins directly from complex samples.”
Standalone sensor option provides workflow flexibility
Alongside the complete kit for guided, automated workflows, Abselion has launched the Tagged Protein Sensor | His-tag Quantification as a standalone consumable pack. This provides direct access to the antibody-coated sensor strips, offering flexibility for a range of His-tag assays on the Amperia platform.
Higgins Qin, senior director of protein and antibody R&D at GenScript, added: “Our THE His Tag Monoclonal Antibodies are recognised for their high affinity and broad applicability across recombinant protein workflows. Incorporating these into Abselion’s Amperia system provides researchers with a solution that simplifies His-tag quantification and supports consistent measurement from crude through to purified samples.”
The product targets applications in drug discovery, structural biology, therapeutic research and bioprocess development workflows.
For more information, visit: https://www.abselion.com/assay-kits/
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