Component-resolved allergy diagnostics
Sensitizations to birch and grass pollens – two of the most common inhalation allergies – can be characterized to a new level of detail using a multiparameter, component-resolved immunoblot test system from EUROIMMUN. The assay employs single purified allergen components (SPAC) for the detection of specific IgE antibodies in place of the usual whole extracts in an approach known as molecular allergology. Th is in-depth profiling enables allergologists to precisely identify diseasecausing allergens, assess the risk of cross allergies and determine patients’ suitability for specific immunotherapy. The immunoblot contains all major allergy-inducing proteins from birch pollen (Bet v1, Bet v2, Bet v4, Bet v6) and grass pollen (Phl p1, Phl p5, Phl p7, Phl p12). In a published study the test successfully verified birch or grass pollen sensitizations in 77 patients with clinically confirmed allergies, and correlated well with comparable commercial assays. Th e assay is based on established EUROLINE technology, which combines economy and efficiency in allergy testing. Only small amounts of sample material are required, and the procedure can be fully automated using innovative devices (EUROBlotMaster, EUROBlotScanner, EUROBlotCamera) and soft ware (EUROLineScan). Th e new EUROLINE SPAC Pollen 1 Profile supplements the EUROLINE portfolio, which offers an extensive range of application-oriented profiles at a very competitive price per allergen.
Supplier: EUROIMMUN AG
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