Automated test for homocysteine
Automated test for homocysteine. An automated test for homocysteine is now available. The test is based on an enzymatic cycling method which
is adaptable to any clinical chemistry analyser. Homocysteine is a sensitive marker for folate and vitamin B12 deficiency and an independent risk factor for cardiovascular diseases. It has also been discussed in connection with other diseases such as birth defects, pregnancy complications, psychiatric disorders and cognitive impairment in the elderly. The standard method of measuring homocysteine has been by chromatography, which is time-consuming, complex and requires special equipment and skills. Other enzymatic assays show critical interference by cystathionine, which is often elevated in dialysis patients. The DiaSys Homocysteine FS is a liquid stable, ready to use reagent. The enzymatic cycling leads to significant enhancement of the substrate and therefore to stable signals and good precision. The test has a measuring range up to 50 µmol/L and is for use with serum or plasma. There is no interference from haemolysis, lipaemia and cystathionine, and it compares well with other methods. Liquid stable calibrators and controls are provided as well as instrument applications for various analysers.
Automated test for homocysteine
Supplier: DiaSys Diagnostic Systems GmbH
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