Assays for the detection of sedative drugs

Three new ELISA testing kits for the detection of sedative drugs Zopiclone, Zaleplon and Zolpidem are now available. These drugs behave in a similar ways to benzodiazepines. The Z drugs are found in prescription medications, however, they should only be used for a short time period as extended use can lead to tolerance. The misuse of Z drugs is widespread as a result of both dependence and recreational use. Incidents of unusual or inappropriate behaviour have been linked to misuse of Z drugs, where the patients had no memory of their actions. Some users have reported sleepwalking, sleep driving, binge eating, and performing other daily tasks while asleep. Randox Toxicology has developed three ELISA kits for the detection of Z drugs in urine and blood specimens. The Zolpidem ELISA offers an unbeatable Limit of Detection (LOD) of 0.4ng/ml in urine and 0.52ng/ ml in blood. The Zopiclone and Zaleplon ELISA kits are the first immunoassays available for the rapid detection of these drugs. Prior to this, the only way to detect Zopiclone and Zaleplon was with timely chromatographic analysis. The company also provides an automated ELISA plate reader, capable of reading 96 wells in 30 seconds. In addition to the Z drug ELISA kits, Randox Toxicology provides a multiplex Biochip Array which targets Zolpidem, Zopiclone, Zaleplon and their metabolites simultaneously from a single, undivided specimen. The advanced multiplex method consolidates ELISA tests onto a small 9x9mm biochip, enhancing the ability for toxicologists to quickly detect these sedatives.

Supplier: Randox Toxicology Ltd

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