by Dr Jacqueline Gosink The international consensus on standardized nomenclature of human epithelial cell (HEp-2 cell) patterns in indirect immunofluorescence (ICAP, www.anapatterns.org) defines fifteen nuclear patterns, nine cytoplasmic patterns and five mitotic patterns which are relevant for the diagnosis of various autoimmune diseases. Furthermore, the consensus stipulates that autoantibodies detected by indirect immunofluorescence on HEp-2 […]

by Dr Jacqueline Gosink In vitro determination of specific IgE is nowadays a central pillar of allergy diagnostics. Specific IgE against up to 54 allergens can be investigated in parallel using the EUROLINE immunoblot system. Individual EUROLINE profiles are targeted to specific indications, encompassing food, inhalation, atopy, insect venoms and pediatrics, while diverse region-specific profiles […]