Biotecnica, a leading manufacturer of peptones has launched a new line of low endotoxin peptones that do not require ultrafiltration. EndoLow Peptones are developed to meet the needs of the biopharmaceutical industry for the production of medications, vaccines, and diagnostic products. They provide a rich source of nitrogen, vitamins, and carbohydrates for cell growth in culture media.
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EndoLow Peptones maintain optimal levels of amino acids, polypeptides and carbohydrates, while minimizing endotoxin levels, preserving all growth factors that are vital for culture development. This new generation of peptones improves cell density and recombinant protein production in cell culture and microbiological fermentation processes.
Three types of EndoLow Peptones are currently available: EndoLow Casein Peptone, EndoLow Meat Peptone (Bovine) and EndoLow Soy Peptone – which is developed with raw materials certified as non-GMO and animal-free.
Studies conducted by Biotecnica’s R&D department show cells grown in media containing EndoLow peptones achieve greater cell density when compared to media prepared with ultrafiltered peptones.
A LAL test for endotoxin level is conducted on every EndoLow Peptone lot to ensure levels are below 200 EU/gr, exceeding industry specifications for ultrafiltered peptones.
Gonzalo Bautista, Head of RD at Oaxaca, Mexicobased Biotecnica, commented: “As a leading manufacturer of biological raw materials for the production of high-quality culture media, including peptones, extracts, infusions and other raw materials of animal and vegetable origin, Biotecnica is well placed to deliver innovations such as this new range of peptones to the global bioprocessing market. The COVID-19 pandemic has put the biopharmaceutical industry in the spotlight and we look forward to supporting our customers with the highest quality peptones as they continue to develop the next generation of medication, vaccines and diagnostics.”