Diatron expands haematology analyser capabilities with six advanced RUO indice
Diatron, a STRATEC brand specialising in the development, manufacturing, and marketing of haematology and clinical chemistry analysers and related reagents for human and veterinary use, has expanded the capabilities of its Aquila, Aquarius 3, and Abacus 5 haematology analysers with six advanced Research Use Only (RUO) indices. The new parameters are automatically derived from existing Complete Blood Count (CBC) data, requiring no additional samples, consumables, or workflow modifications.
The six indices introduced are the Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), Monocyte-to-Lymphocyte Ratio (MLR), Mentzer Index, Red Cell Distribution Width Index (RDWI), and Green & King Index.
Inflammatory and immune status biomarkers
NLR, PLR, and MLR are widely described in the literature as markers that reflect immune and inflammatory status. In research settings, they offer a non-invasive means of investigating systemic inflammation, infection severity, and immune activation, and have been studied across a range of clinical areas including infections, cardiovascular disease, oncology, and autoimmune conditions.
Published literature has reported associations between elevated NLR and outcomes such as infection, cancer prognosis, and cardiovascular risk; between PLR and pro-inflammatory or pro-thrombotic states; and between MLR and chronic inflammatory conditions such as tuberculosis and autoimmune disease.
Differentiation of microcytic anaemias
The Mentzer Index, RDWI, and Green & King Index have been described in the literature as tools to support the differentiation between Iron Deficiency Anaemia (IDA) and Beta-Thalassaemia Trait (BTT). By combining key CBC parameters, these indices can facilitate investigations into diagnostic strategies and algorithms in haematology research.
Note: These parameters are not available in the USA.
Operational integration and research utility
A key operational advantage of the new indices is the elimination of manual calculation. All six parameters are computed automatically from routine CBC results and are presented through the intuitive software interfaces of the Aquila, Aquarius 3, and Abacus 5 analysers, making them immediately accessible without added complexity.
Diatron notes that the indices “integrate seamlessly into routine workflows” and deliver “deeper insights directly from routine Complete Blood Counts without extra costs or workflow burden.” The company says that enhanced CBC insights are achieved “without increasing consumable usage or adding workflow steps.”
The indices are suited to a range of research applications, including retrospective and prospective studies, method comparison and validation projects, and exploratory investigations into novel risk scores and algorithms. Diatron highlights their particular value in resource-limited settings, where access to specialised testing or high-cost assays may be constrained.
With a global footprint spanning more than 110 countries and over 50,000 analysers currently in laboratory use, Diatron positions this expansion as part of its commitment to “continuous innovation” and to enabling “actionable insights from routine tests.”
For more information, visit: www.diatron.com
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