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1571

“Marker genes” reveal deadly secrets of Idiopathic Pulmonary Fibrosis

Researchers cracked the complete genetic code of individual cells in healthy and diseased human lung tissues to find potential new molecular targets for diagnosing and treating the lethal lung disease Idiopathic Pulmonary Fibrosis (IPF). A team of scientists from Cincinnati Children’s Hospital Medical Center, in collaboration with investigators at Cedars-Sinai Medical Center in Los Angeles, […]

1572

Beckman Coulter launches annual CARES award as part of initiative to help people living with HIV/AIDS

Beckman Coulter Life Sciences has launched an international HIV/AIDS award at the 2016 conference for the African Society for Laboratory Medicine (ASLM) recently held in Cape Town, South Africa (December 3 to 8).The annual award is part of the company’s global CARES Initiative dedicated to helping people who are living with HIV/AIDS. Beckman Coulter’s CARES […]

1573

New technique tests therapies for breast cancer metastasis

A new laboratory technique developed by researchers at Baylor College of Medicine and other institutions can rapidly test the effectiveness of treatments for life-threatening breast cancer metastases in bone. “For a number of breast cancer patients, the problem is metastasis – the dissemination of breast tumour cells to other organs – after the primary tumour […]

1574

Gene mutations cause leukaemia, but which ones?

“Mutations are part of life. They are mistakes in a gene like typos in a text message,” said Watanabe-Smith, a postdoctoral fellow with the OHSU Knight Cancer Institute. “But which mutations cause cancer? That’s the real question. And this problem is impossible to understand without a strong model system to test those mutations.” Watanabe-Smith’s research […]

1575

Genetic marker found for resistance to malaria treatment in Cambodia

Scientists at the Wellcome Trust Sanger Institute and their collaborators have discovered genetic markers in malaria parasites linked with resistance to the anti-malarial drug piperaquine. This research will allow health officials to monitor the spread of resistance, and help doctors and public health officers decide where the treatment is most likely to be effective. Resistance […]

1576

Philips and LabPON plan to create world’s largest pathology database of annotated tissue images for deep learning

Royal Philips and LabPON, the first clinical laboratory to transition to 100% histopathology digital diagnosis, recently announced its plans to create a digital database of massive aggregated sets of annotated pathology images and big data utilizing Philips IntelliSite Pathology Solution. The database will provide pathologists with a wealth of clinical information for the development of […]

1577

New lab-on-a-chip platform seeks to improve pathogen detection

Researchers from the Fraunhofer Institute have developed a new prototype lab-on-a-chip platform for the easy and versatile detection of molecular pathogens. Nuclear amplification testing is commonly used for pathogen detection; however, the process is currently manually intensive and complex, and requires dedicated equipment. This prevents its use in some settings, and pathogen detection in individual […]

1578

Personalized therapies for the most common birth defect among newborns

Specific genetic errors that trigger congenital heart disease (CHD) in humans can be reproduced reliably in Drosophila melanogaster – the common fruit fly – an initial step toward personalized therapies for patients in the future. “Studying CHD in fruit flies provides a fast and simple first step in understanding the roles that individual genes play […]

1579

Study supporting glycated CD59 as a novel alternative for gestational diabetes screening

Mellitus, LLC reported the publication of results from a prospective, investigator-initiated study conducted at Brigham and Women’s Hospital (BWH) demonstrating the potential clinical utility of glycated CD59 (GCD59) as a novel biomarker for the screening and diagnosis of gestational diabetes mellitus (GDM). The data from this study showed that a single blood test that measures […]

1580

New biomarker is higher in suicide attempters and associated with stress response

Researchers at Lund and Malmö universities in Sweden have measured a biomarker in cell-free blood plasma which can be linked to an overactive stress system in suicidal individuals. This biomarker can hopefully be used in future psychiatric studies. “We don’t expect the marker to be able to predict who will try to commit suicide, but […]