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1731

Blood test spots tumour-derived DNA in people with early-stage cancer

In a bid to detect cancers early and in a non-invasive way, scientists at the Johns Hopkins Kimmel Cancer Center report they have developed a test that spots tiny amounts of cancer-specific DNA in blood and have used it to accurately identify more than half of 138 people with relatively early-stage colorectal, breast, lung and […]

1732

Inflammatory biomarkers indicating brain injury

Researchers at the University of Birmingham have identified inflammatory biomarkers which indicate whether the brain has suffered injury. The team, led by Professor Antonio Belli, at the University’s College of Medical and Dental Sciences, now hopes to use these new biomarkers to develop a test which can be used on the side of a sports […]

1733

HORIBA Medical and Siemens Healthineers enter into agreement to expand laboratory hematology offerings

HORIBA Medical and Siemens Healthineers have entered into a long-term agreement. The companies will collaborate in bringing new and innovative hematology solutions to the market globally. With HORIBA Medical as the original equipment manufacturer to complement the Siemens Healthineers portfolio, the companies will provide customers with expanded options to fulfill their hematology and multidisciplinary solution […]

1734

Scientists identify gene that controls immune response to chronic viral infections

For nearly 20 years, Tatyana Golovkina, PhD, a microbiologist, geneticist and immunologist at the University of Chicago, has been working on a particularly thorny problem: Why are some people and animals able to fend off persistent viral infections while others can’t? Mice from a strain called I/LnJ are especially good at this. They can control […]

1735

Test is first to identify patients with completely benign pancreatic abnormalities

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. The lesions almost never progress to cancer, so patients may be spared unnecessary pancreatic cancer screenings or operations. The two-test combination is the only one to date that can accurately […]

1736

Post-conception mutations may play an important role in autism

Over the past decade, mutations in more than 60 different genes have been linked with autism spectrum disorder, including de novo mutations, which occur spontaneously and aren’t inherited. But much of autism still remains unexplained.A new study of nearly 6,000 families implicates a hard-to-find category of de novo mutations: those that occur after conception and […]

1737

Blood test to detect brain metastases while still tratable

Houston Methodist cancer researchers are now closer to creating a blood test that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time. The discovery of identifying a distinct group of cells in the bloodstream of patients who have […]

1738

Studies open up possibility of immunotherapy for more cancer patients

Tens of thousands of cancer patients each year may benefit from an immunotherapy regimen called PD-1 blockade, based on results from a new clinical study. The findings establish genetic markers that help physicians identify which patients might respond to the therapy, which had been approved previously for a select few classes of cancer. "What we […]

1739

TAILORx trial finds most women with early breast cancer do not benefit from chemotherapy

 New findings from the groundbreaking Trial Assigning Individualized Options for Treatment (Rx), or TAILORx trial, show no benefit from chemotherapy for 70 percent of women with the most common type of breast cancer. The study found that for women with hormone receptor (HR)-positive, HER2-negative, axillary lymph node-negative breast cancer, treatment with chemotherapy and hormone therapy […]

1740

Parkinson’s gene initiates disease outside of the brain

Until very recently, Parkinson’s had been thought a disease that starts in the brain, destroying motion centres and resulting in the tremors and loss of movement. New research shows the most common Parkinson’s gene mutation may change how immune cells react to generic infections like colds, which in turn trigger the inflammatory reaction in the […]