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1751

EKF procalcitonin assay validated for Beckman AU chemistry analysers

EKF Diagnostics announces that its Stanbio Chemistry Procalcitonin (PCT) LiquiColor® assay has been FDA cleared and validated for use on Beckman AU 480, 680 and 5800 clinical chemistry analysers.  EKF is pleased to confirm the immediate availability of a user-defined application (UDA) for running this 10-minute test for bacterial infection and sepsis on these Beckman […]

1752

New methods for genetics analyses and diagnosis of inflammatory bowel disease

The two most common types of inflammatory bowel diseases are ulcerous colitis and Crohn’s disease. These are diagnosed by camera inside the gut, and by investigating small samples of the gut (biopsies). The diagnosis is often difficult, and if the wrong diagnosis is made, there may be severe consequences for the patients, because the treatments […]

1753

Medical researchers find protein that marks difference between cancer and non-cancer cells

A discovery sheds light on how cancerous cells differ from healthy ones, and could lead to the development of new strategies for therapeutic intervention for difficult-to-treat cancers in the future. An international team of investigators found a “stop sign”—a modified protein researchers named a PIP-stop—inside cells that are overused by cancerous cells that effectively prevents […]

1754

Researchers advance technique to detect ovarian cancer

Researchers at Rice University and the University of Texas MD Anderson Cancer Center have refined and, for the first time, run in vivo tests of a method that may allow nanotube-based probes to locate specific tumours in the body. Their ability to pinpoint tumours with sub-millimetre accuracy could eventually improve early detection and treatment of […]

1755

Researchers take a step closer to developing a DNA test for liver cancer

A group of researchers from Mayo Clinic and Exact Sciences Corporation have completed a phase II study comparing a set of DNA markers to alpha fetoprotein as a method to test for liver cancer. “We currently test for liver cancer using ultrasound and a blood protein marker called alpha fetoprotein,” says John Kisiel, M.D., a […]

1756

Genetic variants linked to type 2 diabetes identified in Chinese populations

Researchers investigated genomes from diverse Chinese populations to identify new and known genetic variants that contribute to a person’s blood sugar level and risk of Type 2 diabetes. Karen Mohlke at the University of North Carolina at Chapel Hill, Wei Huang at the Chinese National Human Genome Center and Shanghai Industrial Technology Institute, and their […]

1757

Cancer’s gene-determined “immune landscape” dictates progression of prostate tumours

The field of immunotherapy – the harnessing of patients’ own immune systems to fend off cancer – is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumours result in distinct paths of disease progression and response to therapy. Now, researchers […]

1758

Study provides more clarity on the genetic causes of children’s food allergies

What role do genes play in egg, milk, and nut allergies? A study, led by the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin, has found five genetic risk loci that point to the importance of skin and mucous membrane barriers and the immune system in the development of food allergies. […]

1759

Blood mutations could contaminate genetic analyses of tumours

Genetic mutations in blood cells that have made their way into tumours could be red herrings that mislead physicians looking for genetic changes in tumours that are helping to drive the cancer. This finding is significant because physicians could make misinformed treatment decisions. University of North Carolina Lineberger Comprehensive Cancer Center researchers and colleagues will […]

1760

Gene-based test for urine detects, monitors bladder cancer

Researchers at The Johns Hopkins Kimmel Cancer Center have developed a test for urine, gathered during a routine procedure, to detect DNA mutations identified with urothelial cancers. UroSEEK uses urine samples to seek out mutations in 11 genes or the presence of abnormal numbers of chromosomes that would indicate the presence of DNA associated with […]