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Archive for category: Featured Articles

Featured Articles

shutterstock 2246531485

Epigenetics and pancreatic cancer

, 6 July 2023/in Featured Articles /by panglobal

Pancreatic cancer is a devastating disease, usually first diagnosed at a late stage when the opportunity for the most effective therapy has been missed, and survival rates have not improved for decades. Early detection of the disease is crucial for giving patients the chance of therapy, but, so far, the search for serum protein biomarkers […]

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https://clinlabint.com/wp-content/uploads/sites/2/2023/07/shutterstock_2246531485.jpg 1229 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-07-06 09:58:072023-07-06 10:19:51Epigenetics and pancreatic cancer
ECCMID 2024 will take place 27-30 April 2024 in Barcelona, Spain.

Gilead Sciences announces positive results from Veklury and obeldesivir trials

, 26 May 2023/in Featured Articles /by panglobal

Gilead Sciences announces positive results from Veklury and obeldesivir trials Gilead Sciences, announced positive results from several COVID-19 clinical and real-world evidence studies presented at ECCMID. A Phase 3 clinical study demonstrated that Veklury (remdesivir) was generally well tolerated in people with moderate to severe renal impairment. Additional data includes a retrospective real-world study which […]

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https://clinlabint.com/wp-content/uploads/sites/2/2023/05/ECCMID4.jpg 1180 1512 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-05-26 10:09:032023-05-26 10:09:03Gilead Sciences announces positive results from Veklury and obeldesivir trials
Axcella Therapeutics presents results from Phase 2a clinical trial of AXA1125 for treatment of Long COVID Fatigue

Axcella Therapeutics presents results from Phase 2a clinical trial of AXA1125 for treatment of Long COVID Fatigue

, 26 May 2023/in Featured Articles /by panglobal

Axcella Therapeutics presents results from Phase 2a clinical trial of AXA1125 for treatment of Long COVID Fatigue Axcella Therapeutics – a clinical-stage biotechnology company pioneering novel approaches to treating complex diseases using multi-targeted endogenous metabolic modulator (EMM) compositions – gave two oral presentations of results from the Phase 2a clinical trial of AXA1125 in the […]

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https://clinlabint.com/wp-content/uploads/sites/2/2023/05/ECCMID2.jpg 1390 1412 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-05-26 10:04:382023-05-26 10:04:38Axcella Therapeutics presents results from Phase 2a clinical trial of AXA1125 for treatment of Long COVID Fatigue
ECCMID ESCMID

Shionogi demonstrates efficacy of cefiderocol against difficult-to-treat Gram-negative bacterial infections

, 26 May 2023/in Featured Articles /by panglobal

Shionogi demonstrates efficacy of cefiderocol against difficult-to-treat Gram-negative bacterial infections At ECCMID 2023, Osaka, Japan-based Shionogi announced key data for cefiderocol, an innovative siderophore cephalosporin, including new real-world evidence demonstrating its efficacy against some of the most difficult-to-treat Gram-negative bacterial infections.

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https://clinlabint.com/wp-content/uploads/sites/2/2023/05/ECCMID_logo.png 644 1136 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-05-26 09:57:132023-05-26 09:57:13Shionogi demonstrates efficacy of cefiderocol against difficult-to-treat Gram-negative bacterial infections
ELITech showcases new high throughput sample-to-result instrument for molecular diagnostics

ELITech showcases new high throughput sample-to-result instrument for molecular diagnostics

, 26 May 2023/in Featured Articles /by panglobal

ELITech showcases new high throughput sample-to-result instrument for molecular diagnostics Also at ECCMID, ELITech Group unveiled the upcoming launch of a new high throughput sample-to-result instrument for molecular diagnostics.

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Influential ECCMID 2023 sees numerous scientific presentations

Influential ECCMID 2023 sees numerous scientific presentations

, 26 May 2023/in Featured Articles /by panglobal

Influential ECCMID 2023 sees numerous scientific presentations The 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) took place in Copenhagen, Denmark, 15-18 April 2023. With around 14,000 professional attendees ECCMID is the largest international meeting of clinical microbiologists and infectious diseases specialists. The event included a comprehensive scientific programme, an industry programme and […]

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https://clinlabint.com/wp-content/uploads/sites/2/2023/05/ECCMID3.jpg 1478 1780 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-05-26 09:44:462023-05-26 09:55:22Influential ECCMID 2023 sees numerous scientific presentations
Figure 1. Calibrator and control positioning in robot racks

Faster throughput – together | New streamlined solution for immunosuppressant analysis by LC-MS/MS

, 26 May 2023/in Featured Articles /by panglobal

Faster throughput – together | New streamlined solution for immunosuppressant analysis by LC-MS/MS by Mikaël Levi To face increasing demands on their time and resources, chemical laboratories need easier-to-handle solutions with faster turnaround times, lower costs per sample and full compliance with ever-stricter regulatory standards. Recent work by Alsachim using Shimadzu equipment and software has […]

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https://clinlabint.com/wp-content/uploads/sites/2/2023/05/Figure_1_CMYK.jpg 1440 1920 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-05-26 09:18:342023-05-26 09:32:38Faster throughput – together | New streamlined solution for immunosuppressant analysis by LC-MS/MS
Biomarkers and preanalytics in Alzheimer’s disease

Biomarkers and preanalytics in Alzheimer’s disease

, 26 May 2023/in Featured Articles /by panglobal

by Dr Jacqueline Gosink Biomarkers and preanalytics in Alzheimer’s disease Analysis of biomarkers such as amyloid-beta peptides and tau proteins in cerebrospinal fluid (CSF) is nowadays a core criterion in Alzheimer’s disease diagnostics. Test methods such as ELISA and chemiluminescence immunoassay enable robust and reproducible measurement of the analytes in patient CSF samples. Recommendations for […]

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Figure 1. Respondents gained a variety of INTEGRA pipetting solutions during the pandemic to handle high sample numbers

Responding to a global health crisis: the evolution of the lab

, 26 May 2023/in Featured Articles /by panglobal

by Dr Éva Mészáros Responding to a global health crisis: the evolution of the lab The COVID-19 pandemic forced life sciences laboratories all over the world to suddenly begin high volume PCR testing, to help gain the upper hand over this deadly disease. Many facilities had to adopt new pipetting platforms at short notice to […]

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https://clinlabint.com/wp-content/uploads/sites/2/2023/05/Graph-00.jpg 451 900 panglobal https://clinlabint.com/wp-content/uploads/sites/2/2020/06/clinlab-logo.png panglobal2023-05-26 07:40:382023-05-26 08:16:29Responding to a global health crisis: the evolution of the lab
Four saliva samples containing SARS-CoV-2 RNA were mixed with target-specific capture oligonucleotides attached to magnetic beads. The solutions were heated to 95°C for 1 minute, then placed in a rack with a magnet. After 3 minutes the supernatants were replaced with a 1-step RT-qPCR master mix and subjected to a rapid cycling protocol (1 second at 95°C/1 second at 65°C). The same concentration of four pure RNA samples were amplified at the same time and acted as positive controls. the RNA extracted from saliva recorded the same quantification cycles (blue) as the untreated control RNA (red).

Remodelling qPCR as a tool for molecular diagnostics

, 26 May 2023/in Featured Articles /by panglobal

by Professor Stephen Bustin   Remodelling qPCR as a tool for molecular diagnostics PCR is an incredibly powerful tool in the field of molecular diagnostics, and its current role is embedded in the clinical laboratory where it is indispensable for non-time-critical routine testing. However, point-of-care testing via lateral flow devices, as seen in the recent […]

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Bio-Rad - Preparing for a Stress-free QC Audit

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