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LITERATURE REVIEW: Renal disease
Urinary kidney injury molecule-1 in renal diseaseMoresco RN, Bochi GV, Stein CS, De Carvalho JAM, Cembranel BM, Bollick YS. Clin Chim Acta 2018; 487: 15–21 Kidney injury molecule-1 (KIM-1), a type l transmembrane glycoprotein, is recognized as a potential biomarker for detection of tubular injury in the main renal diseases. Urinary KIM-1 increases rapidly upon […]
Detection of urinary microRNAs as biomarkers of diabetic kidney disease
Current measures for diagnosis and therapy of chronic kidney disease are limited. Better biomarkers are required to improve treatment by directing therapeutic intervention, tracking responses to therapy and providing greater understanding of the underlying mechanisms driving renal disease progression. We describe here the development of microRNAs as biomarkers for diabetic kidney disease, the most common […]
Point-of-care testing for HbA1c: clinical need and analytical quality
HbA1c plays an essential role in the diagnosis and management of people with diabetes. Point-of-care testing for HbA1c offers a wealth of opportunities to provide a rapid, accurate and easy to access tool for healthcare professionals, with performance of some devices matching or even outperforming routine laboratory instruments. by Dr Emma English, Larissa-Nele Schaffert and […]
Detection and typing of HPV for cervical cancer prevention according to Meijer criteria
HPV testing is a linchpin of cervical cancer prevention, providing an effective alternative to the long-standing Pap test. The HPV analysis should encompass all relevant anogenital HPV types and differentiate between high-risk types, which can induce cancer, and low-risk types, which cause benign genital warts. It is also critical to identify multiple and persistent infections, […]