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The last two volumes were devoted to anticoagulants (parenteral, then oral). Now the Clinical Development Department has turned its attention to the exploration of bleeding disorders.The aim of this series launched in 2014 with the objective of publishing one volume each year, is to provide health professionals with clear and comprehensive medical and scientific information […]
The rising incidence of Acute Kidney Injury (AKI) comes at a price. Patients tend to survive intensive care (ICU) but will be discharged with various degrees of chronic kidney disease (CKD), placing an increasing strain on the healthcare system. At present, the cost to the NHS is estimated to be between £434 and £620 million […]
Detection of viruses in clinical samples by use of metagenomic sequencing and targeted sequence captureWylie KM, Wylie TN, Buller R, Herter B, Cannella MT, Storch GA. J Clin Microbiol 2018; 56(12): pii: e01123-1Metagenomic shotgun sequencing (MSS) is a revolutionary approach to viral diagnostic testing that allows simultaneous detection of a broad range of viruses, detailed […]
The presence of hemoglobin (hemolysis), bilirubin (icterus) and lipids (lipemia) in serum can affect the measurement and reporting of many clinical chemistry laboratory test results. This is not only in the validity of the test results themselves, but also whether a result is, or should be, reported. Quality assurance of serum indices is not as […]
Pre-eclampsia is a condition that affects approximately 2–8% pregnancies worldwide and, although the cause is not really understood, is thought to be due to poor function of the placenta. Early signs that create suspicion of pre-eclampsia in the mother typically include hypertension, proteinuria and edema (particularly of the pitting type) of the ankles. Symptoms of […]
Standard drug testing is regularly carried out using urine, blood or oral fluid. However, fingerprints present a good alternative, as the sample collection is non-invasive, rapid and safe. Herein, we describe the application of two different testing methods for the detection of cocaine in fingerprint samples. by Dr Catia Costa, Dr Mahado Ismail and Dr […]
Acute interstitial nephritis (AIN) may be the cause of more than 15 % of instances of acute loss of kidney function. Diagnosed early, it can often be successfully treated; however, lack of obvious symptoms means it can be easily missed. Left untreated, AIN can progress to chronic kidney disease. Currently, clinical diagnosis is confirmed by […]
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