Volatile organic compounds (VOCs) are released from our bodies in our breath, sweat, blood and urine as a result of metabolic activity and so provide a window on our metabolic and physiological status. These VOCs change in response to disease, providing the potential for disease-specific VOCs in the breath to be used as non-invasive biomarkers […]
What is multiple myeloma? Multiple myeloma (also called myeloma) is the over-proliferation of abnormal plasma cells (which normally make antibodies) in the bone marrow (Figs 1&2).
Iron deficiency and iron deficiency anemia are remarkably common worldwide. However, recommended ferritin cut-off concentrations can vary widely and there is room for improvement in standardization across different assay platforms. Dr Katie Troike and Dr Adam McShane (Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA) recently conducted their own re-evaluation of ferritin […]
Assessment of minimal residual disease during B-cell precursor acute lymphoblastic leukemia provides a good indication of therapy response and prognosis. This investigation can be done in several ways, including flow cytometry. Techniques in this field have developed in recent years and CLI chatted to Dr van der Velden (Department of Immunology, Erasmus University Medical Center, […]
The congenital neutropenia syndromes are rare conditions caused by mutations in genes associated with various cell processes. While their clinical presentations may overlap, their natural histories vary. Accurate diagnosis of the genetic etiology of specific conditions is crucial for providing individually tailored management, as the different syndromes have different risk profiles for progression to bone […]
Thermo Fisher Scientific has introduced a groundbreaking solution for more precise blood genotyping in clinical research. The Applied Biosystems™ Axiom™ BloodGenomiX™ Array and Software offers a single, high-throughput assay capable of detecting most extended and rare blood groups, as well as tissue (HLA) and platelet (HPA) types.
Using ferritin as a biomarker for hemophagocytic lymphohistiocytosis can reduce delays in treatment due to negative or pending hemophagocytosis results
Beckman Coulter Diagnostics, a leader in clinical diagnostics, has extended the menu of DxI 9000 Immunoassay Analyzer assays. Recently, tests for Hepatitis B and C viruses – namely Access anti-HCV, Access HBsAg, and Access HBsAg Confirmatory assays – received CE marks.
ProBioGen, a global Contract Development & Manufacturing Organization (CDMO), is partnering with DIOSynVax to manufacture DIOS-HFVac3, a trivalent haemorrhagic fever (HF) vaccine that was developed in collaboration with Prof. Dr. Ralf Wagners team at the Institute of Medical Microbiology and Hygiene, University of Regensburg. The novel vaccine targets HF diseases caused by Ebola, Marburg, and […]
November 2025
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