Human ANGPTL-4 ELISA kit

Angiopoietinlike protein 4 (ANGPTL4), a member of the angiopoietin- like gene family, is a 406 amino acid protein with a molecular weight of 50 kDa. It is a circulating protein predominantly expressed in adipose tissue and liver, and also occurs in heart, skeletal muscles and intestines. ANGPT4 inhibits LPL and retards lipoprotein catabolism. The expression of ANGPTL4 is reported to be dramatically upregulated by hypoxic stress in endothelial cells, cardiomyocytes and tumours. In patients with type 2 diabetes, serum levels of ANGPTL4 were found to be significantly lower than those in healthy subjects, suggesting that the decreased ANGPTL4 could be a causative factor of this disease. The potential angiogenic activity of ANGPTL4 may be important in rheumatoid arthritis. The Human ANGPTL4 ELISA kit extends BioVendor’s portfolio of diagnostic kits for lipoprotein metabolism and DM2T. With serum and plasma (citrate, EDTA) samples, the 96 well-microtitre plate format is suitable for use with standard ELISA equipment.

Supplier: BioVendor Research and Diagnostic Products

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