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Leica Biosystems unveils high-speed laser cassette printer for histology

Leica Biosystems, a Danaher company, has launched globally the HistoCore LIGHTNING C Laser Cassette Printer, a system designed to help pathology laboratories standardise histology workflows, improve traceability and move from sample to answer with greater speed and certainty.

Identification at the front end of the workflow

Leica Biosystems points to rising case volumes, increasing test complexity and persistent staffing constraints facing pathology laboratories. Small inefficiencies in early workflow steps can, it says, create large downstream delays, rework and risk, and traditional labelling methods can introduce inconsistency, manual steps and ongoing maintenance demands. As laboratories advance digital pathology and explore AI-enabled tools, the company adds, consistency and traceability at the front end become increasingly important to the quality of downstream images, data and diagnostic insights.

Speed, durability and integration

Leica Biosystems describes the printer as delivering fast, consistent and durable specimen identification at the very start of the histology workflow. It is designed for use with validated Leica Biosystems cassettes and uses UV laser printing to produce clear, durable markings, including barcodes and 2D codes, to support traceability from processing through diagnosis. Key features include:
• Printing speeds of up to 2.5 seconds per cassette and capacity for up to 600 cassettes, intended to optimise through-put, reduce bottlenecks and maintain workflow continuity under growing demand
• No ink or ribbons reduces maintenance requirements and downtime and lowers total cost of ownership
• Automated colour recognition and LIS compatibility, matching cassette colour to predefined templates to reduce manual intervention and help prevent identification errors

“Histology laboratories are often expected to do more with limited time, space and resources, while still needing confidence that every specimen is accurately identified across the diagnostic journey,” said Anupama Mokkapati, senior vice president of Core Portfolio and Global Supply Chain at Leica Biosystems. “The HistoCore LIGHTNING C Laser Cassette Printer helps laboratories enhance foundational workflow steps by combining speed, durable print quality and seamless integration to support accurate, timely results to patients.”

As part of Danaher’s connected ecosystem of life sciences and diagnostics companies, Leica Biosystems said it supports nearly 2 million cancer tests globally each week and is the only provider of end-to-end solutions across the anatomic pathology workflow.

The printer was showcased at the

National Society for Histotechnology (NSH) Convention in San Antonio, Texas, from 25 to 29 September 2026. The company notes that the cassettes included are intended for in vitro diagnostic use only.

For more information, visit: www.leicabiosystems.com

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Leica Biosystems HistoCore LIGHTNING

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