by Dr Jacqueline Gosink Bone turnover markers (BTMs) provide a non-invasive method to assess bone remodelling – the process by which old bone tissue is removed and replaced. Measurement of BTMs supports diagnosis of metabolic bone diseases, such as Paget’s disease, and is a useful aid for monitoring therapy responses in osteoporosis. Panels of peptide […]
New research identifies interleukin-6 as a superior diagnostic biomarker for sepsis in high-risk populations including neonates, children, and pregnant women.
Two prominent European biospecimen and life sciences companies have combined to strengthen research capabilities across Europe and North America, marking significant expansion in biospecimen services and stem cell research sectors.
Cellular Origins, a TTP company specialising in cell and gene therapy (CGT) manufacturing solutions, has announced the acquisition of the Autologous Cell Therapy Industrial Automation (ACTIA) Platform intellectual property. The acquisition is set to augment the company’s existing Constellation™ platform, which was launched in May 2023.
A unique portfolio of neurobiomarker tests The testing landscape for neurological diseases has expanded rapidly in recent years due to the characterisation of many novel biomarkers. With over 15 years of experience in neurological analytics, EUROIMMUN offers an unparalleled portfolio of assays for determination of more than 80 neurobiomarkers in autoimmune diseases, neurological infections and […]
In a significant move for gene therapy research, Annogen has announced a collaboration with Orchard Therapeutics to identify immune cell-specific human promoters for use in certain pre-clinical hematopoietic stem cell (HSC) gene therapy programmes. This partnership aims to advance the development of more targeted and potentially safer gene therapies for central nervous system (CNS) disorders.
Researchers at Moffitt Cancer Center have developed a novel method for the scalable synthesis of withanolides, a class of naturally occurring compounds with significant potential in cancer treatment. This groundbreaking approach, published in Science Advances [1], could revolutionise cancer research by providing a reliable and efficient means of producing these vital compounds in large quantities.
Scientists at King’s College London have developed a rapid method for creating cyclic peptides, potentially accelerating the production of new antibiotics to combat antimicrobial resistance (AMR). The research, published in the Journal of the American Chemical Society [1], demonstrates a technique that reduces synthesis time from hours or days to mere minutes.
The association of epigenetic changes with disease pathogenesis is the subject of much study. CLI caught up with Dr Kathleen Barnes (Oxford Nanopore Technologies) to find out more about how DNA methylation is linked to disease as well as developments in methods of DNA methylation analysis for improving disease diagnosis, prognostic stratification and therapy.
By Dr Stephen Langabeer The myeloproliferative neoplasms of polycythemia vera, essential thrombocythemia and primary myelofibrosis are clonal hematopoietic disorders characterized by an over-production of mature blood cells. Molecular evaluation is a key component of differentiating malignancy from a host of reactive causes with mutations in JAK2, CALR and MPL genes present in the majority of […]
November 2025
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