The association of epigenetic changes with disease pathogenesis is the subject of much study. CLI caught up with Dr Kathleen Barnes (Oxford Nanopore Technologies) to find out more about how DNA methylation is linked to disease as well as developments in methods of DNA methylation analysis for improving disease diagnosis, prognostic stratification and therapy.
By Dr Stephen Langabeer The myeloproliferative neoplasms of polycythemia vera, essential thrombocythemia and primary myelofibrosis are clonal hematopoietic disorders characterized by an over-production of mature blood cells. Molecular evaluation is a key component of differentiating malignancy from a host of reactive causes with mutations in JAK2, CALR and MPL genes present in the majority of […]
Produced using a patented dry-spinning technology – CollaFibR from AMSBIO is a highly consistent collagen fibre matrix that closely mimics the biomechanical and biochemical properties of natural collagen scaffolds, offering an accurate representation of in-vivo conditions.
Researchers from Insilico Medicine and NVIDIA have developed a novel large language model (LLM) called nach0 that can understand and generate both biomedical text and chemical structural data.
May 2026
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