A complete range of kits for the testing of urinary proteins is available. Such tests are particularly useful from a diagnostic viewpoint, providing important information for the diagnosis of renal diseases, monitoring and differential analysis of proteinurias. All reagents are latex-based, ready-to-use and validated according to the international CLSI protocols. Within the range, urinary-Transferrin, urinary-Albumin (micro-albuminuria), and urinary-IgG, are of paramount importance. Albuminuria is one of the most important markers for damages to the endothelium. Pathological levels of urinary albumin (micro-albuminuria) are present in diabetes, hypertension, and during the early stages of preeclampsia. Transferrin and albumin together are pathognomonic of selective glomerular proteinuria. If the IgG levels rise the glomerular proteinuria becomes non selective. The accuracy guaranteed by the method allows correct calculation of the Cameron index (ratio between IgG clearance and transferrin clearance). The urinary proteins kits are available as both turbidimetry and nephelometry. The dedicated product lines include calibrators and controls whose assigned values are in accordance with International Scientific Committee’s guidelines. All urine testing products from Sclavo are available in specific formats and packaging developed for all Sclavo Systems (Sclavo Palio, Dirui, Konelab), Sclavo EasyNeph (nephelometry), in addition to the multi-purpose format. Along with specific proteins kits, the company offers a dedicated kit for testing total urinary proteins, highly sensitive to both tubular proteins, as well as Bence-Jones proteinuria, ensuring reliable and accurate results.

Read more

Various Fecal occult blood tests (FOBTs) are available, however, many have a high rate of inaccuracies and false positives.  The Hemosure iFOBT (FIT) -fecal immunochemical test- doesn’t require drug or diet restrictions, only one test is needed and it has a higher patient compliance rate. A rapid, convenient and odourless qualitative, sandwich dye conjugate immunoassay, the test employs a unique combination of monoclonal and polyclonal antibodies to selectively identify elevated levels of human hemoglobin as low as 50 ng / mL in five minutes. It is a useful aid in the diagnosis of gastrointestinal (GI) bleeding in a number of GI disorders, e.g. diverticulitis, colitis, polyps, and colorectal cancer. The immunochemical test is specific to human hemoglobin and reduces false positives while offering the correct level of specificity and sensitivity for accurate reading.

Read more

Human African Trypanosomiasis (HAT) or sleeping sickness is a life threatening neglected tropical infection affecting rural population in sub-Saharan Africa. The disease causes severe neurological disorders often leading to death if not treated. Since years, HAT control has been facilitated by the Card Agglutination Test for Trypanosomiasis (CATT/T.b.gambiense), which is particularly suited for large scale screening. But now, with the steadily decreasing prevalence of HAT, specificity becomes a critical parameter. Furthermore, the target population lives in precarious conditions (without electricity) and this test must be robust enough to be carried out in very difficult conditions. A new diagnostic test stable at ambient temperature, cheap and that can be performed with minimal training is the best solution.  To fulfil all these requirements, Coris BioConcept has developed the “HAT Sero K-SeT”, which has been successfully validated in the DR of Congo (specificity of 98,6 % ; sensitivity of 98,5 % ; n=493).

Read more

Takyon is the new Eurogentec qPCR line developed to give access to a new level of speed in qPCR applications. Its name is inspired by the faster than light particle (Tachyon). Emerging from the combination of an optimized reaction buffer and a new efficient enzyme, Takyon for SYBR and Probe Assays ensure sensitivity and fast delivery of accurate and reproducible results. With Takyon qPCR Kits, amplification is achieved with a very short extension time of 15 seconds, enabling clear detection of low copy targets also on difficult templates together with excellent reproducibility across the different runs of the same template. Available as MasterMixes and Core Kits, Takyon kits possess universal capabilities. Combined with the company’s inert Blue Dye, it enhances visualization and reveals to the naked eye dispensing errors that may occur during assay set-up.

Read more