The determination of Zinc in seminal plasma, together with the reagent for Citrate and Fructose complete the Biosystems line for the diagnostic evaluation of human fertility. Zinc is used as a marker of the secretory function of the prostate gland. Low values indicate an abnormal disruption of the secretory function, possibly as a result of obstruction of the conducts due to acute or chronic inflammation. The determination of zinc in serum provides information about the metabolism of proteins and nucleic acids, and the functioning of the immune system, which is required for wound healing. A severe blood zinc deficiency is linked with depressed growth and stunting and increases the incidence of infectious diseases. Less severe zinc deficiencies are linked with immune function disorder, diarrhea, altered cognition, alopecia, vision defects and other adverse clinical conditions. Ingestion of a zinc-contaminated diet involves high blood concentrations and is associated with abdominal pain, diarrhea and nausea. Heparinized plasma samples are preferred to serum for zinc analysis to avoid possible zinc contamination from erythrocytes, platelets and leukocytes during clotting and centrifugation.
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Automated chemiluminescence immunoassay system
, /in Product News /by 3wmediaThe MAGLUMI 800 CLIA analyser offers excellent performance to medium or small-sized laboratories. It has been designed with a small size, but still provides high operating performance, through its high capacity for samples (40 with direct barcode reading) and for 9 reagents with a throughput of 180 tests/hour. Easy operation via PC touch screen, continuous loading and 24 hours ready to use facilitate routine and special immunoassay. Moreover, a clot detector and liquid level detector guarantee accurate results. Three operation modes, Random, Batch and STAT, as well as user-friendly software ensure easy-to-use testing options and data management. The refrigerated system assures all the 110 test parameters perform well at all times.
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Rapid test for Helicobacter pylori detection
, /in Product News /by 3wmediaNow available is an improved liquid method for H. pylori detection from biopsy samples, the Helicobacter pylori UFT300 quick test. The detection is based on the detection of bacterial urease activity in gastric biopsy specimens. A gastric mucosa colonized by H. pylori is invariably inflamed, and can lead to atrophic gastritis, which has been linked with peptic ulcer and gastric cancer, two of the most important diseases of the upper gastrointestinal tract. The quick test is easy to store and perform and results are ready in a few minutes, enabling diagnosis and reporting at the point of gastroscopy.
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Cellular analysis line
, /in Product News /by 3wmediaUsing unique technology, the SC-120 slide maker and stainer is able to make blood films, print the barcodes and other patient information directly onto the slides, stain them with different types of staining protocols and dry their wet surfaces. A total of 120 slides can be processed per hour. The stained slides, ready for microscopy, are loaded in cassettes located at the unloading area. The MindrayOmniLab CAL 8000 hematology system combines the BC-6800 hematology analyser with the SC-120 slide maker and stainer into one comprehensive workstation. With the possibility to include up to four BC-6800s and two SC-120s, the system can be scaled-up to meet the workload requirements of even large labs. Manual interruptions are minimized as the workflow of the SC-120 allows user-defined staining protocols and enables users to define decision rules. The resultant efficient workflow and higher reliability of the system reduce operating costs as well.
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New generation Alzheimer’s diagnostics
, /in Product News /by 3wmediaA new generation of ELISAs provides standardized, automated analysis of beta-amyloid (Aß) peptides (Aß 1-42 and Aß 1-40) and total tau (T-tau) proteins in cerebrospinal fl uid (CSF), facilitating diagnosis of Alzheimer’s disease in its early stages. The concentrations of these biomarkers reflect the Alzheimer’s-specific neuropathological changes in the brain. A significant decrease in Aß 1-42 is observed as many as 5 to 10 years before the start of cognitive changes. Aß 1-40 remains unchanged. The determination of the ratio Aß 1-42 to Aß 1-40 increases the efficiency of early diagnostics and might help to discriminate Alzheimer’s disease from vascular dementia. The concentrations of T-tau and phosphorylated tau (P-tau) increase when patients develop advanced neurodegeneration and cognitive impairment. Th e Aß 1-42, Aß 1-40 and T-tau ELISAs have been developed by Euroimmun in collaboration with ADx Neurosciences. They are based on a sandwich principle employing well-characterized capture antibodies. This matrix-independent methodology ensures extremely high consistency in results. The assays are CE-certified and include lyophilized calibrators for added convenience and precision. The procedures are highly standardized and can be automated on Euroimmun analysers and other open ELISA platforms.
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HIV combo assay
, /in Product News /by 3wmediaMainly intended for use in blood banks or laboratories, the Enzygnost HIV Integral 4 is an HIV combination test (or HIV Combo test), a type of assay that detects both the HIV p24 antigen and HIV antibodies, and is increasingly becoming the standard screening technique used by healthcare authorities in many countries within the European Union. The assay delivers both excellent specificity and sensitivity. In a study of 14,169 donor samples tested at three different blood banks, initial specificity was demonstrated at 99.94 percent. Data also show that the HIV Integral 4 assay has higher sensitivity and provides superior seroconversion performance (quicker prevalence of the antibody) compared to other currently available assays, detecting HIV infection up to 14 days earlier. The new assay is available on the Quadriga BeFree and BEP Siemens laboratory systems.
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Zinc reagent
, /in Product News /by 3wmediaThe determination of Zinc in seminal plasma, together with the reagent for Citrate and Fructose complete the Biosystems line for the diagnostic evaluation of human fertility. Zinc is used as a marker of the secretory function of the prostate gland. Low values indicate an abnormal disruption of the secretory function, possibly as a result of obstruction of the conducts due to acute or chronic inflammation. The determination of zinc in serum provides information about the metabolism of proteins and nucleic acids, and the functioning of the immune system, which is required for wound healing. A severe blood zinc deficiency is linked with depressed growth and stunting and increases the incidence of infectious diseases. Less severe zinc deficiencies are linked with immune function disorder, diarrhea, altered cognition, alopecia, vision defects and other adverse clinical conditions. Ingestion of a zinc-contaminated diet involves high blood concentrations and is associated with abdominal pain, diarrhea and nausea. Heparinized plasma samples are preferred to serum for zinc analysis to avoid possible zinc contamination from erythrocytes, platelets and leukocytes during clotting and centrifugation.
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5-part differential automated hematology analyser
, /in Product News /by 3wmediaThe newly launched DS- 600/600i 5-Part Differential Automated Hematology Analyzer adopts dual channel cell analysis system and uses only 10uL sample volume to obtain 29 parameters, 2 histograms and 2 scatter grams. Advanced semiconductor laser and flow cytometry combined with excellent chemical staining reagents make the results more accurate and reliable.
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Platelet-derived supplement for cell culture
, /in Product News /by 3wmediaEntirely of human origin for in vitro cell culture applications, Lysex enables selection, expansion and differentiation of human primary cell cultures, such as adult and fetal mesenchymal stem cells (MSC), skin fibroblasts, articular chondrocytes, osteoblasts, adipose-derived cells. It enhances cell proliferation, maintaining the differentiation potential in cells otherwise difficult to expand in culture such as articular chondrocytes from elderly donors and allows culture of cells in a xeno-free environment (as it completely eliminates the need of fetal bovine serum). The fully standardized and lyophilized two-component system allows easy optimization of culture conditions for any cell type directly by the user.
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Blood cell counter
, /in Product News /by 3wmediaDesigned for labs that work under difficult conditions, this 3-population, 60-test/hour blood cell counter functions in all environments and continually delivers excellent results at an affordable rate for labs. Extremely reliable, the Countender 20+ exhibits zero technical failures during the first 2 years and a mean time between failures of minimum 2 years on average. Its robustness is its greatest attribute. Featuring 20 parameters and 3 histograms, the COUNTENDER 20+ is equipped with ELENOR, an electronic noise reduction system that ensures very accurate platelet counts. An integrated data management system allows operators to easily compile coordinated reports. This blood cell counter also has one of the lowest consumption rates of reagents on the market. Coupled with simplified maintenance operations and the long shelf-life of SFRI dedicated reagents (up to 36 months), the instrument has low servicing requirements and significantly reduces the cost of tests for labs.
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Randox Homocysteine- Innovative diagnostic testing
, /in Product News /by 3wmediaThe Randox Homocysteine assay offers laboratories a convenient two-part, liquid ready-to-use option for the accurate determination of Homocysteine concentrations in serum or plasma. Additional benefits associated with Randox Homocysteine include two levels of calibrator included in the kit for user convenience; limited interference helping ensure accurate and reliable results are returned; and an extensive measuring range of 1.74-47.9 µmol/l facilitating comfortable detection of abnormal levels related to all Homocysteine associated disease states. Furthermore, Randox Homocysteine is suitable for use on a variety of clinical chemistry analyzers via a range of instrument specific applications.
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