Amino Sign is a point of care analyser to measure lysine easily and quickly. Lysine, or L-lysine, is an essential amino acid. That means it is necessary for human health, but the body can’t manufacture it, so the only sources are dietary, including supplements. Amino acids like lysine are the building blocks of protein. Lysine is important for proper growth, and it plays an essential role in the production of carnitine, a nutrient responsible for converting fatty acids into energy and helping to lower cholesterol. Lysine appears to help the body absorb calcium, and it plays an important role in the formation of collagen, a substance important for bones and connective tissues including skin, tendon, and cartilage. Most people get enough lysine in their diet, although athletes, vegans who don’t eat beans, as well as burn patients may need more. Not enough lysine can cause fatigue, nausea, dizziness, loss of appetite, agitation, bloodshot eyes, slow growth, anemia, and reproductive disorders. For vegans, legumes (beans, peas, and lentils) are the best sources of lysine. Amino Sign uses the Lysine Card test strip in a 4-step procedure to measure lysine concentration in whole blood specimens. Sample volume is 5μL and the test is performed in two minutes. The pocket size analyzer’s dimensions are 115x58x20mm.
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Platelet-derived supplement for cell culture
, /in Product News /by 3wmediaEntirely of human origin for in vitro cell culture applications, Lysex enables selection, expansion and differentiation of human primary cell cultures, such as adult and fetal mesenchymal stem cells (MSC), skin fibroblasts, articular chondrocytes, osteoblasts, adipose-derived cells. It enhances cell proliferation, maintaining the differentiation potential in cells otherwise difficult to expand in culture such as articular chondrocytes from elderly donors and allows culture of cells in a xeno-free environment (as it completely eliminates the need of fetal bovine serum). The fully standardized and lyophilized two-component system allows easy optimization of culture conditions for any cell type directly by the user.
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Blood cell counter
, /in Product News /by 3wmediaDesigned for labs that work under difficult conditions, this 3-population, 60-test/hour blood cell counter functions in all environments and continually delivers excellent results at an affordable rate for labs. Extremely reliable, the Countender 20+ exhibits zero technical failures during the first 2 years and a mean time between failures of minimum 2 years on average. Its robustness is its greatest attribute. Featuring 20 parameters and 3 histograms, the COUNTENDER 20+ is equipped with ELENOR, an electronic noise reduction system that ensures very accurate platelet counts. An integrated data management system allows operators to easily compile coordinated reports. This blood cell counter also has one of the lowest consumption rates of reagents on the market. Coupled with simplified maintenance operations and the long shelf-life of SFRI dedicated reagents (up to 36 months), the instrument has low servicing requirements and significantly reduces the cost of tests for labs.
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Randox Homocysteine- Innovative diagnostic testing
, /in Product News /by 3wmediaThe Randox Homocysteine assay offers laboratories a convenient two-part, liquid ready-to-use option for the accurate determination of Homocysteine concentrations in serum or plasma. Additional benefits associated with Randox Homocysteine include two levels of calibrator included in the kit for user convenience; limited interference helping ensure accurate and reliable results are returned; and an extensive measuring range of 1.74-47.9 µmol/l facilitating comfortable detection of abnormal levels related to all Homocysteine associated disease states. Furthermore, Randox Homocysteine is suitable for use on a variety of clinical chemistry analyzers via a range of instrument specific applications.
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New ‘Supermix’ Chemistry Control
, /in Product News /by 3wmediaSpecifically designed to replace multiple instrument specific controls the new Liquid Assayed Chemistry Premium Plus control from Randox uniquely combines 100 analytes including proteins, lipids, cardiac markers, drugs and immunoassays in a single vial to help clinical laboratories reduce valuable time and costs without compromising on performance or quality.
As a third party control laboratories are assured of a truly unbiased, independent assessment of performance. With the added advantages associated with liquid controls and the availability of assayed target values for a range of platforms this control will enhance performance and productivity in any clinical laboratory.
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High throughput automated coagulation system
, /in Product News /by 3wmediaThe new Coapresta 2000 (CP2000) is an automated system with a small footprint, high-throughput and a range of dedicated barcoded reagents. The system can run up to 400 PT tests per hour. Test panels include PT, APTT, Fibrinogen, D-dimer, FDP, AT and many other new assays are in development. The system offers excellent performance, predominately ready-to-use liquid reagents, and can be interfaced to LAS systems using point- in-space sampling, which make it an exciting new choice for laboratories seeking an efficient, high performing coagulation solution. The system is the market leading product in the higher volume system category in Japan, where it was developed. The CP2000 Coagulation System is available for purchase in Europe, Middle East and Africa through the Sekisui Diagnostics offices in Kent, UK and Rüsselsheim, Germany as of January 2014.
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Combination cell/microbead autoantibody IFT assay
, /in Product News /by 3wmediaThe novel CytoBead technology offers for the first time the combination of autoantibody analysis by cell-based screening and the confirmation of the corresponding autoantigen reactivities by multiplexing, using the immunofluorescence technique (IFT) in one reaction environment. The CytoBead ANCA for example allows the screening of antineutrophil cytoplamsic antibodies (ANCA) on ethanol-fixed neutrophiles and the confirmation thereof using proteinase 3 (PR3) and myeloperoxidase (MPO) coated microbeads. Furthermore, the detection of Goodpasture antibodies, which can occur in 10% of rapid progressive glomerulonephritis patients, is integrated by adding glomerular basement membrane (GBM) coated microbeads. Additionally, this technology provides an ideal reaction environment for multiplexing antinuclear antibody (ANA) assessment and the detection of celiac disease specific antibodies. This assay format can be interpreted with a standard fluorescence microscope for semi-quantitative analysis and with the automated interpretation system Aklides for quantitative testing. CytoBead technology is an attractive alternative to classical, time-consuming single parameter antibody detection and is applicable for high throughput routine diagnostics.
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Troponin I point-of-care test has obtained CE marking
, /in Product News /by 3wmediaThe ESC, ACCF, AHA and WHF stipulate that Troponin assays should demonstrate a coefficient of variation (CV) of 10% or less at the 99th percentile of the normal population, which no prior POC device could do. The high sensitivity Meritas test achieves a CV of 10% at 36pg/ml which is the 99th percentile. Results are available patient-side within 15 minutes and the Meritas analyser uses only a single drop of whole blood in a one-step process. This test will, for the first time, allow doctors to evaluate potential MI patients quickly and accurately. With CE marking achieved, Trinity Biotech now intends to release the product for sale in Europe and other carefully selected markets through its specialist cardiology distributor network.
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Genetic testing prevents abacavir hypersensitivity in HIV patients
, /in Product News /by 3wmediaThe genetic risk of abacavir hypersensitivity in HIV patients can be established in whole blood samples using a new microarray based on EUROArray Direct technology. The DNA test identifies the presence of the HLAB* 57:01 allele, which is the main genetic factor associated with adverse reactions to abacavir-containing drugs. The EUROArray HLA-B*57:01 analysis is fast and simple and does not require any in-depth molecular biology knowledge. Gene sections are first amplified from the samples by multiplex polymerase chain reaction (PCR). The use of whole blood as starting material significantly reduces the costs and hands-on time required. The PCR products are then incubated with Biochip microarray slides containing immobilized complementary DNA probes. Results are evaluated and interpreted fully automatically by specialized software (EUROArrayScan). Meticulously designed primers, ready-to-use PCR components and integrated controls all contribute to the reliability of the analysis. In studies using precharacterized samples, the microarray demonstrated 100% sensitivity and 100% specificity. Abacavir is an important chemotherapeutic agent for the treatment of HIV patients. Nevertheless hypersensitivity reactions occur in 48-61% of Caucasian, 8-16% of black African and 20-22% of Hispanic carriers of the HLA-B*57:01 allele undergoing treatment, compared to 0-4% of non-carriers. Therefore, all HIV-infected patients, regardless of their ethnicity, should be tested for the presence of the HLA-B*57:01 allele before starting treatment with drugs containing abacavir sulphate (e.g. Ziagen tablets and suspension, Kivexa tablets and Trizavir tablets).
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New stabilizer for urine specimens
, /in Product News /by 3wmediaThe stabilization of urine is most important if the specimen cannot be analysed within two hours. A particular problem is exponential bacterial growth, since certain bacteria divide every 20 minutes. This can lead to an overgrowth of pathogenic bacteria, making detection difficult. Furthermore, the lysis of cells is accelerated in native urine at room temperature, altering the concentration of various analytes constantly. This problem is essential for longer transportation and processing times. It has been shown, that on average 15% of urine samples intended for urine culture are contaminated. Some additives that may have been used up to now for stabilization have proven not to be optimal, as oft en the additive does not dissolve quickly or fully. The new Vacuette Urine CCM tube contains a stabilizer in powder form, which keeps the urine sample stable for up to 48 hours at 20 – 25°C. During this time period, the urine specimen can be stored or transported without refrigeration. All mandatory and facultative uropathogenic bacteria can be stabilized and reliably detected in the Vacuette Urine CCM tube for up to 48 hours. A particular advantage is the high solubility of the stabilizer in powder form. By inverting the tube several times, the urine mixes completely with the stabilizer additive, ensuring quick stabilization of the urine sample. The tube can be used for urine screening (strip test, sediment, clinical chemistry) and/or for microbiology, since sample stability is guaranteed for up to 48 hours. The extensive application in urine diagnostics makes daily routine work easier and more efficient: one urine sample for a broad range of determinations. This is not only an advantage for medical staff but also for the patient. Made from shatter-proof, highly transparent PET plastic, the Vacuette Urine CCM tube with safety cap is user-friendly as it is especially easy to open. This allows for a hygienic operating method, with no risk of splashes or aerosols.
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Point of care lysine analyser
, /in Product News /by 3wmediaAmino Sign is a point of care analyser to measure lysine easily and quickly. Lysine, or L-lysine, is an essential amino acid. That means it is necessary for human health, but the body can’t manufacture it, so the only sources are dietary, including supplements. Amino acids like lysine are the building blocks of protein. Lysine is important for proper growth, and it plays an essential role in the production of carnitine, a nutrient responsible for converting fatty acids into energy and helping to lower cholesterol. Lysine appears to help the body absorb calcium, and it plays an important role in the formation of collagen, a substance important for bones and connective tissues including skin, tendon, and cartilage. Most people get enough lysine in their diet, although athletes, vegans who don’t eat beans, as well as burn patients may need more. Not enough lysine can cause fatigue, nausea, dizziness, loss of appetite, agitation, bloodshot eyes, slow growth, anemia, and reproductive disorders. For vegans, legumes (beans, peas, and lentils) are the best sources of lysine. Amino Sign uses the Lysine Card test strip in a 4-step procedure to measure lysine concentration in whole blood specimens. Sample volume is 5μL and the test is performed in two minutes. The pocket size analyzer’s dimensions are 115x58x20mm.
Read more