Siemens Healthcare Diagnostics is introducing a first-of-its-kind, handheld portable coagulation analyser. The Xprecia Stride coagulation analyser delivers fast, reliable Prothrombin time testing (PT/INR) for point-of-care monitoring and management of oral anticoagulation therapy (OAT) with warfarin, a vitamin K antagonist. The Xprecia Stride coagulation analyser was specifically designed to meet the growing demand for fast and reliable PT/INR results in physician offices and walk-in clinics to help healthcare professionals make informed decisions about patient care.

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The LCMS-8060 triple quadrupole mass spectrometer is designed to push the limits of LC/MS/MS quantitation for applications requiring the highest sensitivity and robustness while delivering a meaningful solution for routine LC/MS/MS analyses. It detects substances at ultra-trace level as they occur in complex matrices for example, or in smallest sample concentrations which have to be diluted in order to avoid matrix effects. The LCMS-8060 is the newest member of Shimadzu’s UFMS (Ultra-Fast Mass Spectrometry) family and part of the Shimadzu mass spectrometry platform of MS/MS systems with ultra-fast technologies. The system combines a heated ESI source with all UF technologies including UFsweeper III, a collision cell filled with argon gas. Through its high speed technology, UFsweeper III achieves dwell times of 0.8 ms per MRM. With new UF Qarray ion guide technology increasing ion production and signal intensity, the LCMS-8060 introduces a new level of sensitivity and makes a real difference to working better and faster. The system features a data acquisition scan speed of 30,000 u/sec and a polarity switching time of 5 msec. The newly developed UF Qarray boosts ion sensitivity while suppressing noise. By improving the ion sampling device, ion guide and vacuum efficiency, the instrument achieves unprecedented sensitivity in LCMS.  Shimadzu’s proprietary technologies allow acquisition of up to 555 MRM channels per second, ultra-fast polarity switching and ultra-fast scanning, all with highest data quality.  Robustness of the LCMS-8060 and modified ion optics was assessed by injecting 2,400 samples of femtogram levels of alprazolam spiked into protein-precipitated human plasma extracts over a six day period (over 400 samples were injected each day). RSD of peak area response was 5 % over this test period, and use of a deuterated internal standard (alprazolam-d5) led to RSD of 3.5 %. As part of the robustness test the vacuum system was vented to model a transient power failure, with however no effect on signal response or baseline noise level.

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The i-chroma^TM Reader is a portable scanning instrument for measuring the concentration of target analytes in human blood; urine and other specimens.
The system consists of fluorescence readers and test cartridges and can be used to screen cardiac diseases; cancers; diabetes; infectious diseases and hormonal disorders.

• Cardiac tests are: Troponin; D-Dimer; CK-MB; Myoglobin and HsCRP.
• Cancer tests are: PSA; AFP; CEA and iFOB.
• Diabetes tests are: HbA1C and Microalbumin.
• Hormone tests are: Cortisol; hCG; B-HCG; LH; TSH; T3; T4; Prolactin; Testosterone; FSH; Progesterone and Vitamin D 25 (OH) D.
• Rheumatoid Arthritis tests are: RF(IgM) and ASO.
• Infection tests are: CRP; HsCRP and Procalcitonin.
• A number of the tests can be carried out using whole blood and therefore no separation is required.  These are: Troponin; CK-MB; Myoglobin; HsCRP; PSA; AFP; HbA1C; Cortisol; RF(IgM) and CRP.

^{All products are CE marked}

Specifications
Dimensions: 250x185x80 mm
Weight: 1.2 kgs
Interface: RS232 (serial port)
Key pads: 5 function keys
LIS/HIS connection via PC
Thermal printer (optional)
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The AFS 40E / 80E / 120E and 150E water purification systems have been developed to provide clinical laboratories with an economical and reliable water purification solution for daily water volumes of up to 3000 L. They rely on two powerful technologies to produce water quality meeting Clinical and Laboratory Standards Institute (CLSI) clinical laboratory reagent water standards. State-of-the-art, proven Elix electrodeionization (EDI) technology ensures constant water quality with low and predictable running costs, while unique E.R.A. (Evolutive Reject Adjustment) technology takes feed water quality into account in order to automatically optimize water recovery – and reduce water usage costs. The AFS 40E / 80E / 120E and 150E systems also offer users powerful 24/7 real-time monitoring and remote control over their water purification systems, as well as a new generation of enhanced services. These advanced monitoring features, along with an unprecedented level of service, also help maximize water purification system and analyser uptime. The systems have been designed to provide quick and precise remote diagnostics and offer proactive service in order to avoid downtime. Service starts with feed water analysis by a certified Merck Millipore field service engineer prior to system installation. Then, over time, users can ensure the best upkeep of their AFS E water purification system with a customized Watercare Pact service plan. With its large new touch screen, the system is designed for intuitive operation and for supporting the user with easy step-by-step instructions during routine maintenance. For increased flexibility, the system interface can also be accessed from another location, using a PC, tablet, or smart phone through a web browser. Mobile and customizable, the new range of systems is designed to make the best use of lab space. The quiet, compact systems are mounted on wheels, and can be moved around the lab – or to another location – depending on current lab requirements. AFS E system users can choose from a number of options and accessories to match their specific requirements, including an online Total Organic Carbon (TOC) monitor, degassing option, and sanitary sampling valve, among others.
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Antibodies against chikungunya virus (CHIKV) can be detected with high sensitivity and specificity using new ELISA and indirect immunofluorescence test (IIFT) systems from EUROIMMUN. Serological analysis is an important supplement to direct pathogen testing in the diagnosis of CHIKV infections, especially given the short viremic phase. Antibodies against CHIKV are detectable from 6 to 8 days after onset of clinical symptoms, when direct detection is generally no longer effective. The determination of CHIKV antigens or anti-CHIKV IgM antibodies is, moreover, of major importance in the screening of blood reserves. The Anti-Chikungunya Virus ELISA (IgM) is a fully automatable test for the detection of acute infections. The assay is based on recombinant structural proteins from CHIKV and shows 100% sensitivity, as demonstrated with clinically characterized samples. The Anti-Chikungunya Virus ELISA (IgG) is based on the same antigen and is used to demonstrate seroconversion following infection with the virus. A four-fold IgG titre increase between acute and convalescence samples taken at least 14 days apart indicates an acute infection. The Anti-Chikungunya Virus IIFT (IgM or IgG) utilizes virus-infected cells for detection of specific antibodies. In the Arboviral Fever Mosiac 1 IIFT, the CHIKV substrate is combined with other arbovirus substrates for the differential diagnosis of CHIKV infections from e.g. dengue virus or Japanese encephalitis virus infections, which often show similar clinical symptoms.

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