Although your instruments may automatically detect HIL interferences, shouldn’t the lab’s QC program include pre-analytical checks to monitor instruments’ ability to detect them? Studies show that interferences from hemolysed, icteric or lipemic (HIL) specimens are amongst the most common pre-analytical errors.  Liquichek Serum Indices is a quality indicator intended for use as part of laboratory interference testing to monitor an instrument’s ability to detect these three types of samples. Replicating relevant concentrations of HIL interferences using human-sourced materials will allow confidence in the instrument’s performance. With Bio-Rad’s Unity Interlaboratory Program, the user is able to compare instrument responses among peer groups to help avoid costly test repeats. https://tinyurl.com/yxpmoe2e
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ioLight, creator of the world’s first high-resolution portable microscope, has now designed a new compact inverted microscope for cell culture observation in the lab. This very compact, lightweight and robust inverted microscope is even tough enough for use inside an incubator. The ioLight inverted microscope is just 170mm in size and sealed to protect the inner workings. This means it is perfectly suited to observing cell culture in a lab incubator without having to open the door. Cell development is monitored by an inverted microscope, with the lens underneath the petri dish looking upwards into the sample with illuminators both above and below the sample. Because the inverted microscope accommodates a petri dish, observation of cells and organisms can be achieved using standard laboratory procedures without having to prepare a slide sample. Through a simple Wi-Fi connection, the inverted microscope enables images to be stored on a tablet, mobile phone or laptop and shared instantly with collaborators anywhere. The ioLight inverted microscope uses both bright field and dark field illumination. Bright field mode illuminates high contrast samples from above, displaying them against a bright background. Dark field mode illuminates lower contrast or even transparent samples with scattered light, highlighting them against a dark background. This allows a wide range of samples to be imaged. The ioLight inverted microscope is a cost-effective and compact laboratory tool that is really simple to use. Users have the ability to view images on a mobile phone and because it is wireless they can leave the microscope inside an incubator so they do not have to disrupt the experimental conditions.
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Respons940 is a random access analyser with a true throughput of 400 tests/hour (640 tests/hour with ISE) irrespective of whether mono- or 2-component tests are performed. With an onboard capacity of 36 different methods in mono- or twin containers, 50 barcoded samples plus 30 positions for calibrators, controls or emergency samples, respons940 offers superior flexibility in organizing laboratory workflows. Ready-to-use reagents, one-grip loading of reagent containers, integrated bar code reader for samples and reagents, durable hard glass cuvettes, a maintenance-free photometric unit as well as a modern software interface turn respons940 into an allround system for everyday use. Owing to low reagent consumption and the proven quality of DiaSys reagents with long-term stability and broad measuring ranges which minimizes the need for re-runs, respons940 constitutes an economical analyser for medium-sized laboratories.
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The EurobioPlex HSV-1, HSV-2 and VZV kit, which obtained the CE mark, is a real-time amplification test of viral DNA of each of these viruses, with specific detection, as well as a DNA extraction and PCR inhibition control. This ready to use test is performed from extracted DNA, or directly on cerebrospinal fluid (CSF) without extraction using a reaction in a single well/tube. The test is indicated to detect and specifically differentiate the DNA of these viruses, and thus to diagnose the occurrence of infection by these viruses in humans, or to supplement a proven or undetermined diagnosis. Time from sample to result is short: less than 35 min. on standard PCR instruments such as CFX96 (Bio-Rad) or LC480 (Roche), and 1h on the 8-well, single-patient testing TCOR8-IVD instrument (Tetracore), networkable (WiFi/Ethernet) for remote access and data download. The Eurobio-Plex HSV1-HSV2-VZV has been validated on the following specimens: plasma, blood, amniotic fluid, various biological samples with cellular components (skin, eye, pharynx, tongue, colon, penis, foreskin, anogenital and vaginal areas, naso-pharyngeal aspirations), and directly on CSF.
Human herpesviruses are enveloped linear double-stranded DNA viruses belonging to the family Herpesviridae. Their DNA replication and transcription of their genes occur in the nucleus of infected cells. They are subdivided into three groups: alpha-, beta – and gamma herpesviridae. Primary infection with herpes virus is common and most infections occur during childhood. Many Infections with varying degrees can occur at any age, resulting in various diseases: skin lesion (herpes eczema), encephalitis, neonatal herpes and disseminated herpes. A special case is that of VZV, responsible for chickenpox, characterized by moderate fever and a vesicular eruption. Generally benign for children, there is a risk of severe complications when it is contracted by adults, immunosuppressed people and pregnant women. The reactivation of the virus in the body leads to the appearance of zona. Fast direct detection from CSF with EurobioPlex HSV1-HSV2-VZV constitutes a powerful tool for the diagnosis of meningitis.
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KLoneus®, the TRIMERO’s new generation of Kappa and Lambda free light chain assays, based on polyclonal specific antibodies, has been developed specifically to quantify serum and “non-concentrated” urine samples on clinical chemistry analysers, by particle enhanced turbidimetric method. Assay parameters are available for the most extended analysers.
In order to ensure lot-to-lot consistent results, values have been traced to the European Reference Material ERM-DA470k/IFCC (Institute for Reference Materials and Measurements, IRMM).
Other available turbidimetric assays include IgD Immunoglobulins, bound & free light chains for serum and urine, C1q Complement, C5 Complement, C1 (Esterase) Inhibitor, Factor B (C3 Proactivator), Retinol Binding Protein (RBP) for serum and urine, Soluble Transferrin Receptor (sTfR), Hemopexin, Cystatin-C for serum and urine, Serum Amyloid A (SAA),…
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