Monoclonal antibodies (mAb) are important components of CE-marked IVD reagents used in diagnosis of diseases and follow-up of treatment. DIAsource Immunoassays, a BioVendor group company, recently announced the launch of 13 new antibodies for IVD applications: Adiponectin, FABP4, COMP, NT-ProANP, Uromodulin, Soluble Transferrin Receptor, Placental Protein 13, Cathepsin K and Procalcitonin antibodies are now available and offered to the IVD providers for development of Immunoassays. This follows the launches of novel Vitamin D conjugates, Vitamin D dissociation buffers, and antibodies against ACTH, PTH, IGF-1, Testosterone and Progesterone. All these antibodies were developed with special focus on sensitivity, selectivity and stability to ensure long-term supply. They are produced and fully automatically purified under strict ISO 9001 – ISO 13485 conditions. Products are available in purified unconjugated format. Large scale productions can be guaranteed in state-of-the-art facilities. DIAsource is continuously expanding its product portfolio with niche, high valued parameters and these new launches consolidate its actual position on the market, with an enlarged portfolio of proven and performing antibodies for IVD providers.
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New CE-marked chemiluminescence immunoassays (ChLIA) for detection of antibodies against Borrelia, Epstein-Barr virus (EBV-CA, EBNA), proteinase 3 (PR3) and phospholipase A2 receptor (PLA2R) on the EUROIMMUN RA Analyzer 10 system are available now. Different immunoglobulin classes can be analysed depending on the application, with assays encompassing anti-Borrelia IgG and IgM, anti-EBV-CA IgG and IgM, anti-EBNA IgG, anti-PR3 IgG and anti-PLA2R IgG. The random access system, used in conjunction with the ChLIA products, functions as a compact automation solution in small- to medium-sized laboratories, or complements high-throughput-devices in large-sized laboratories. Test- and lot-specific information, including stored standard curves, are imported into the database by means of an RFID code, enabling error-free and convenient loading, along with efficient and secure test evaluation. The EURO-IMMUN RA Analyzer 10 allows continuous loading — also as part of a laboratory track system — to ensure that every sample is processed with minimal effort as a single determination. The ChLIA technology offers short reaction times, with total analysis in 30 minutes or less. In addition, the preferred processing of emergency samples (STAT) gives laboratories with different requirements and sample volumes flexibility in their laboratory routine.
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Type 2 diabetes mellitus (T2DM) now attains the status of global pandemic, spreading from developed to developing countries. The epidemiological trends indicate that the prevalence will continue to increase dramatically. The World Health Organization estimates diabetes to be the seventh global leading cause of death, accounting for 1.6 million deaths in 2016. Randox is committed to advancing diabetes testing, including the associated complications. Randox offers a comprehensive range of high quality reagents ranging from diabetes risk assessment, diagnosis and monitoring of diabetes, and monitoring of associated complications. The Randox diabetes portfolio covers the full spectrum of clinical biochemistry laboratory testing requirements including several superior performance and unique assays. Applications are available detailing instrument-specific settings for a wide range of clinical chemistry analysers. https://www.randox.com/diabetes-reagents/
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The Access PCT assay is the latest addition to the menu for the Access family of im-munoassay systems. The state-of-the-art sensitivity and low-end precision of Access PCT assay combined with short incubation time helps physicians in the risk assessment of critically ill patients in danger of progression to severe sepsis or septic shock, with test results available in under 20 minutes. Procalcitonin levels in blood have been found to correlate with the severity of bacterial infections and also with the probability of a positive blood culture, making it a clinically useful marker in the assessment of patients with possible sepsis or septic shock. The ability to rapidly diagnose suspected sepsis patients and determine appropriate care and treatment is critical, as earlier administration of antibiotics is highly correlated with increased patient survival. Access PCT enables healthcare providers to integrate procalcitonin testing analysis into their routine sepsis work-ups on core laboratory analysers, as a primary or reflex test programmed though Beckman Coulter’s REMISOL Advance middleware. Such integration simplifies laboratory workflow and optimizes institutional sepsis management protocols while reducing the operation expense of maintaining costly dedicated instrumentation. The Access PCT assay has received CE mark certification and is avail-
able for use on the Access family of immunoassay systems including the Access 2, UniCel DxI 600 and UniCel DxI 800.

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The VACUETTE FC Mix Tube is specifically designed for reliable detection of diabetes and taking appropriate measures to combat the condition. The citrate/citric acid buffer ensures a quick stabilization of the blood sample. The glycolysis is catalysed and suppressed. Therefore, the blood sugar is held constantly at the in vivo value. Due to the sodium fluoride additive contained in the VACUETTE FC Mix Tube, inhibition is extended to 48 hours. Additionally, Na2-EDTA is included as an anticoagulant, which is effective due to complexation of Ca++. The almost full inhibition of glycolysis in the VACUETTE FC Mix Tube means that diagnosis is a much more reliable process than before. The stabilization is carried out in whole blood and therefore does not require immediate centrifugation. Unlike in tubes with liquid additives, the finely granulated additive does not cause a dilution effect. The breakdown of glucose (glycolysis) in venous blood samples is of great significance in pre-analytics, particularly in relation to the diagnosis of diabetes mellitus and gestational diabetes. To prevent imme-diate glycolysis in the event of delay between blood collection and measurement in the lab, test tubes should include a citrate/citric acid buffer as well as sodium fluoride (NaF).
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