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Press release: INTEGRA’s automated pipetting solutions improve accuracy and reproducibility for microRNA-based diagnostics

MiRXES, a biotechnology company based in Singapore, is relying on a range of INTEGRA pipetting systems to increase the speed and precision of its RT-qPCR workflows. Adam Chiow, Senior Research Officer at MiRXES, explained: “We are using a proprietary RT-qPCR technology platform – ID3EAL™ – to identify new microRNA biomarkers and develop diagnostic kits for the early identification of cancer and infectious diseases.

We therefore routinely perform RT-qPCR on microRNAs extracted from patient samples, and use the INTEGRA VOYAGER adjustable tip spacing pipette to effortlessly transfer samples between 96 and 384 well formats. The automatically adjustable channels of these pipettes fit our workflow perfectly.”

“We are also developing a new kit which will be able to determine the levels of different microRNAs in a person’s body. For this assay we load several samples into a 96-well column format, then we use INTEGRA’s ASSIST PLUS pipetting robot, together with the VOYAGER, to load the samples onto the assay plate in a protected environment. The VIALAB pipette automation software allows us to program the SOP into the pipette, so the steps are carried out the same way every time. Automating the workflow in this way cuts down on manpower needed to run the assay, and ensures that the samples are loaded accurately and reproducibly. This removes the chance of human error affecting the PCR results. One person is able to complete the plate, seal it, and load it into the PCR machine in the same amount of time that it takes for the PCR machine to analyze a plate, making it an almost continuous process.”

MiRXES uses the ASSIST PLUS pipetting robot from INTEGRA to load samples onto plates in preparation for microRNA assays.

Visit the INTEGRA Biosciences website to learn more.

About INTEGRA Biosciences

INTEGRA Biosciences ( is a leading provider of high-quality laboratory tools and consumables for liquid handling and media preparation. The company is committed to creating innovative solutions which fulfil the needs of its customers in research, diagnostics and quality control within the life sciences markets and medical sector. Today, INTEGRA innovative laboratory products are widely used all around the world. More than 100 distribution partners form a worldwide sales network providing responsive and competent services to customers. These distribution partners are supported by a highly motivated and experienced team of specialists at the company headquarters in Zizers, Switzerland and Hudson, NH, USA. INTEGRA is an ISO 9001 certified company.