Historically, bile acids (BAs) were thought of as playing a role in lipid metabolism. In recent years, however, they have been found to affect the body in a much more wide-ranging way and are important in many normal functions and, therefore, also many disease states. CLI chatted to Dr Giovanny Rodriguez Blanco, lab leader at […]
Background Psoriatic arthritis (PsA) has a global incidence of approximately 0.1–0.2% and affects men and women equally. PsA is a chronic, immune-mediated, inflammatory disease, closely linked to psoriasis. Whereas psoriasis is characterized by patches of abnormal skin, PsA affects the joints and often includes damage to the fingernails and or toenails. Around 30% of people […]
What is protein glycosylation? There are several types of post-translational modifications (PTMs) that proteins can undergo. Phosphorylation, methylation and acetylation all involve the addition of small chemical groups which affect function. Ubiquitylation involves the addition of the small peptide, ubiquitin, which targets proteins for degradation. Glycosylation is one of the more complex forms of PTM, […]
By Dr Jacqueline Gosink An emerging drug-resistant pathogen of global concern Candida auris (C. auris) is a globally emerging multidrug-resistant fungal pathogen, which spreads easily in health-care facilities and causes high mortality in vulnerable patients. Of the laboratory methods that can be used for C. auris identification, real-time PCR offers the fastest turnaround time as […]
Beckman Coulter Life Sciences has launched a new high-throughput assay that promises to drastically cut the time required to detect and quantify protein aggregation during monoclonal antibody development.
Shimadzu Corporation has launched the new LCMS-TQ RX Series of triple quadrupole liquid chromatography-mass spectrometry (LC-MS/MS) systems, designed to provide clinical laboratories with greater analytical sensitivity, measurement stability, and operational efficiency.
November 2025
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